【摘要】 目的:探讨输尿管软镜负压鞘在输尿管软镜治疗感染性肾结石患者中的可行性及安全性。方法:选取2017年12月-2019年7月本院收治的98例感染性肾结石患者作为研究对象,采用随机数字表法分为观察组(49例)和对照组(49例)。其中对照组采用输尿管软镜进行碎石,观察组在对照组基础上采用输尿管软镜负压鞘行输尿管软镜碎石治疗。对比两组手术时间、术中出血量、肾盂内压、住院时间、住院费用、术后结石清除率以及并发症发生率。结果:观察组手术时间、住院时间、术中肾盂内压最小值、肾盂内压最大值和平均肾盂内压均低于对照组(P<0.05);两组术中出血量以及住院费用比较,差异均无统计学意义(P>0.05);经手术治疗后,两组一次性清石率均为100%,但观察组术后1个月的结石清除率明显高于对照组(P<0.05),且观察组术后并发症发生率明显低于对照组(P<0.05)。结论:输尿管软镜负压鞘应用于输尿管软镜治疗感染性肾结石,可缩短手术时间,降低肾盂内压力,提高结石清除率,并降低术后并发症发生率,具有较好的可行性、有效性和安全性。更多还原

【Abstract】 Objective: To investigate the feasibility and safety of negative pressure sheath under flexible ureteroscope in the treatment of infectious renal calculi. Method: A total of 98 patients with infectious renal calculi who were admitted to the hospital from December 2017 to July 2019 were enrolled as study objects. They were divided into the observation group(49 cases) and the control group(49 cases) by random number table method. The control group was given flexible ureteroscope for lithotripsy, while the observation group underwent flexible ureteroscopic lithotripsy by flexible ureteroscope vacuum sheath on basis of the control group. The operation time, intraoperative blood loss, intrapelvic pressure, hospitalization time, hospitalization cost, postoperative stone clearance rate and incidence of complications were compared between two groups. Result: The operation time, hospitalization time, intraoperative minimum, maximum and average of intrapelvic pressure in the observation group were lower than those in control group(P<0.05). There were no significant differences in intraoperative blood loss, hospitalization cost between two groups(P>0.05). After surgery, one-time stone clearance rates in both two groups were 100%, however, the stone clearance rate in the observation group was significantly higher than that in control group after 1 month of surgery(P<0.05), while the postoperative complication rate of the observation group was significantly lower than that in control group(P<0.05). Conclusion: The application of flexible ureteroscope vacuum sheath in flexible ureteroscopic lithotripsy in the treatment of infectious renal calculi can shorten operation time, reduce intrapelvic pressure, increase calculi clearance rate, and reduce incidence of postoperative complications, with good feasibility, effectiveness and safety.更多还原