【摘要】 目的观察封闭式负压引流(VSD)联合超声清创术(UDM)在糖尿病足(DF)溃疡创面愈合中的应用。方法选取DF溃疡患者153例,按入院先后顺序随机分为VSD联合UDM(VSD+UDM)组77例和VSD组76例。比较两组入院第7天时的细菌清除率、创面面积、创面缩小面积、创面缩小率,以及出院时创面愈合时间、住院时间、换药次数、住院费用和治疗前后经皮氧分压。结果入院第7天,两组比较,VSD+UDM组细菌清除率、创面缩小面积及创面缩小率均高于VSD组,创面面积低于VSD组,差异有统计学意义(P <0.05)。VSD+UDM组创面愈合时间、换药次数及住院费用均低于VSD组,差异有统计学意义(P <0.05)。两组经皮氧分压比较,治疗前差异无统计学意义(P>0.05),治疗后VSD+UDM组较VSD组增高,差异有统计学意义(P<0.05)。结论 VSD联合UDM治疗DF溃疡可促进创面愈合,缩短创面愈合时间和住院时间,治疗效果较传统换药联合VSD更显著。更多还原

【Abstract】 Objective To observe the effect of ultrasonic debridement machine(UDM) combined with vacuum sealing drainage(VSD) in diabetic foot(DF) ulcer healing. Methods A total of 153 cases with DF ulcer were divided into VSD+UDM group(n = 77) and VSD group(n = 76) according to the order of admission. The bacterial clearance rate, wound surface, wound surface reduction, wound surface reduction rate and other related index were compared. Results The bacterial clearance rate, wound surface reduction and wound surface reduction rate were higher, while wound surface was lower in VSD+UDM group than in VSD group(P < 0.05 or P < 0.01). The surface healing time, dressing times and hospital stays were lower in VSD+UDM group than in VSD group(P < 0.05 or P < 0.01). There was no statistical significance on transcutaneous oxygen pressure before treatment, and compared with VSD group, the transcutaneous oxygen pressure was reduced after treatment. Conclusion UDM combined with VSD in DF ulcer healing can promote wound healing, reduce the healing time, hospital stays and hospitalization costs. The treatment effectiveness of UDM+VSD is more prominent than traditional treatment combined with VSD.更多还原