【摘要】 产气肠杆菌是一种兼性厌氧的革兰阴性杆菌,近年来其耐药现象在临床上较为突出,其引发的感染已成为全世界的主要关注问题。介导产气肠杆菌耐药的机制主要有主动外排系统、膜孔蛋白改变、产β-内酰胺酶及生物膜形成等。了解产气肠杆菌耐药机制将为临床抗菌药物合理使用提供理论依据。本文就其耐药机制的研究进展进行综述。更多还原

【Abstract】 Enterobacter aerogene is a facultative anaerobic Gram-negative bacilli. In recent years, its drug resistant phenomenon is clinically prominent, and the infection caused has become a main concern worldwide. The mechanism of drug resistance of Enterobacter aerogenes included active efflux system, change of membrane pore protein, and production of β-lactamase and biofilm formation. Understanding the resistance mechanism of Enterobacter aerogenes helps provide theoretical basis for the rational use of antibiotics. This paper summarized the research progress in its resistance mechanism.更多还原