【摘要】 目的比较他汀类药物治疗高血脂合并老年动脉粥样硬化性急性脑梗死的临床疗效。方法选取2018年2月至2019年3月我院收治的的60例高血脂合并老年动脉粥样硬化性急性脑梗死患者为研究对象,依据随机数表,随机分为3组,分别是a组应用阿托伐他汀治疗,b组应用瑞舒伐他汀治疗,c组应用辛伐他汀治疗,每组各20例,比较3种药物临床应用效果与不良反应发生率。结果经用药治疗后,3组患者均取得较为理想的治疗效果,患者的空腹血糖、TC、HDL-C、LDL-C、肝功能等指标均有所改善,且差异不明显(P>0.05),在不良反应的对比中,3组患者不良反应均较少,无统计学意义(P>0.05)。结论高血脂合并老年动脉粥样硬化性急性脑梗死患者应用他汀类药物疗效佳,且不良反应较少。更多还原

【Abstract】 Objective To compare the clinical efficacy of statins in the treatment of hyperlipidemia combined with atherosclerotic acute cerebral infarction in the elderly. Methods Sixty patients with hyperlipidemia combined with atherosclerotic acute cerebral infarction admitted to our hospital from February 2018 to March 2019 were randomly divided into three groups according to the random number table. They were treated with atorvastatin in group a, rosuvastatin in group B and simvastatin in group C. Each group had 20 patients. The clinical effects and incidence of adverse reactions of three drugs were compared. Results After treatment, the three groups of patients achieved ideal therapeutic effect. The fasting blood sugar, TC, HDL-C, LDL-C, liver function and other indicators of patients were improved, and the difference was not significant(P>0.05). In the comparison of adverse reactions, the adverse reactions of the three groups were less, and there was no statistical significance(P>0.05). Conclusion Statins are effective in the treatment of hyperlipidemia combined with atherosclerotic acute cerebral infarction in the elderly, with fewer adverse reactions.更多还原