【摘要】 目的分析肺结核合并糖尿病的临床特征和治疗效果。方法纳入我院于2017年2月至2018年2月所接收的肺结核合并糖尿病患者共120例。对所有患者进行临床诊断,同时分析诊断结果,记录临床特征,并比较临床效果。结果①120例患者中,病变出现1个肺段为20.8%,多个肺段79.2%。②涂片阴性42.5%、±以及+10%、++9.2%、+++20%、++++18.3%;③120例患者中,胃肠道不适34例;肝损伤43例;视神经炎10例;关节痛6例;尿酸增高56例;白细胞减少10例;血小板减少2例;药物热和药疹8例;④常规治疗中,有效52例、无效5例、恶化3例、空洞缩小42例、痰菌阴转20例;个体化治疗,上述指标为55例、3例、2例、40例、21例,组间对比无统计学意义(P>0.05)。结论对于肺结核合并糖尿病患者而言,因本身免疫力低,同时并发症多,导致治疗难度提升,因此临床应通过显著特征发现病症,及早治疗。更多还原

【Abstract】 Objective To analyze the clinical features of pulmonary tuberculosis complicated with diabetes and to evaluate treatment effects. Methods A total of 120 cases of pulmonary tuberculosis complicated with diabetes who were treated in Beijing Geriatric Hospital between February 2017 and February 2018 were selected for study. All the patients were clinically diagnosed, diagnostic results were analyzed, clinical features were recorded and clinical outcomes were compared. Results Firstly, Among all the 120 patients, 20.8% suffered from lesion of one pulmonary segment and 79.2% suffered from lesions of multiple pulmonary segments. Secondly, among all the patients, smear rate of negative, ± and +, ++, +++ and ++++ were 42.5%, 10%, 9.2%, 20%, 18.3% respectively. Thirdly, among the120 patients, 34 suffered from gastrointestinal discomfort; 43 suffered from liver injury; 10 suffered from optic neuritis, 6 suffered from joint pain, 56 suffered from uric acid increase, 10 suffered from leukopenia, 2 suffered from thrombocytopenia and 8 suffered from drug-induced fever and drug eruption. Fourthly, among the patients treated with conventional treatment, 52 enjoyed illness alleviation, 5 encountered ineffective treatment, 3 suffered from illness aggravation, 42 cases enjoyed cavity decrease and 20 enjoyed sputum negative conversion. Among the patients treated with personalized treatment, the indicators above were 55, 3, 2, 40 and 21 respectively. There was no significant difference between the groups(P>0.05). Conclusion That it is difficult to treat the patients with pulmonary tuberculosis complicated with diabetes due to their low immunity and many complications. Therefore, they should be diagnosed by outstanding clinical features and treated as early as possible.更多还原