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阿司匹林联合硫酸氢氯吡格雷口服治疗脑梗死的有效性和安全性分析

Efficacy and Safety of Aspirin Combined with Clopidogrel Hydrogen Sulfate in the Treatment of Cerebral Infarction

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【作者】 汪云春

【Author】 WANG Yun-chun;Jilin Provincial People’s Hospital;

【机构】 吉林省人民医院

【摘要】 目的研究分析阿司匹林联合硫酸氢氯吡格雷口服在临床中治疗脑梗死患者的效果以及安全性情况。方法择取在2017年4月至2018年3月到我院就诊的96例脑梗死患者,随机划分为48例A组、48例B组,A组接受阿司匹林治疗,B组接受阿司匹林+硫酸氢氯吡格雷治疗,统计临床治疗有效性以及安全性情况,并进行评价与对比分析。结果 A组临床总有效率为75.00%,B组为95.83%,经对比B组临床总有效率更高(P<0.05);A组不良反应总发生率为16.67%,B组为4.17%,经对比B组不良反应发生率更低(P<0.05)。结论针对脑梗死疾病,选择阿司匹林+硫酸氢氯吡格雷方式进行治疗后,疗效可观,且具有较高的安全性,在临床中具有可观的价值。

【Abstract】 Objective To study the efficacy and safety of aspirin combined with clopidogrel hydrogen sulfate in the treatment of patients with cerebral infarction. Methods Ninety-six patients with cerebral infarction who were admitted to our hospital from April 2017 to March 2018 were randomly assigned to 48 patients in group A and 48 patients in group B. Group A received aspirin therapy, group B accepted aspirin + clopidogrel hydrogen sulfate,statistical clinical treatment effectiveness and safety damage, and evaluation and comparative analysis. Results The total effective rate was 75.00% in group A and 95.83% in group B. The total effective rate was higher in group B than in group B(P<0.05). The total incidence of adverse reactions in group A was 16.67%, and that in group B was 4.17%. The incidence of adverse reactions was lower in the comparison group B(P<0.05). Conclusion For the treatment of cerebral infarction, the choice of aspirin + clopidogrel hydrogen sulfate is effective, and it has high safety and considerable value in clinical practice.

  • 【分类号】R743.3
  • 【被引频次】2
  • 【下载频次】35
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