【摘要】 高尿酸血症主要是由于尿酸排泄能力下降或者合成异常所导致的疾病,近些年来在发病率方面有明显上涨的趋势。人类每日产生的尿酸30%由肠道排出,肾脏则排出70%,因此肾脏的排泄对血尿酸水平起着至关重要的作用,本文综述了国内外尿酸的生成排泄,HUA的患病率现状,HUA的形成机制及影响尿酸排泄的相关因素等临床相关问题的研究进展。更多还原

【Abstract】 Hyperuricemia is mainly caused by decrease of uric acid excretion capacity or abnormal synthesis. In recent years, hyperuricemia incidence shows significant increase trend. 30% daily uric acid of human is excreted with intestine and 70% with kidneys. Therefore, kidneys excretion plays an important role for blood uric acid level. The article reviews research progress on related clinical issues home and abroad, including production and excretion of uric acid, prevalence of HUA, formation mechanism of HUA and related factors affecting excretion of uric acid.更多还原