【摘要】 目的探讨替吉奥联合顺铂治疗晚期胃癌的疗效。方法选取2015年3月至2018年1月间陕西省渭南市潼关县人民医院收治的84例晚期胃癌患者,采用随机数表法分为研究组和对照组,每组42例,研究组患者采用替吉奥联合顺铂治疗,对照组患者采用5-氟尿嘧啶联合顺铂治疗,采用实体瘤疗效评价标准进行疗效评估,比较两组治疗结果。结果研究组患者的总有效率为78. 6%,明显高于对照组患者的64. 3%,差异有统计学意义(P <0. 05)。研究组患者的不良反应发生率为11. 9%,明显低于对照组患者的26. 2%,差异有统计学意义(P <0. 05)。结论替吉奥联合顺铂治疗晚期胃癌的效果明显,可减少不良反应产生率,安全性高,促进病情快速稳定。更多还原

【Abstract】 Objective To study the efficacy of tegafur plus cisplatin in the treatment of advanced gastric cancer. Methods A total of 84 patients with advanced gastric cancer admitted to Tongguan County People’s Hospital from March 2015 to January 2018 were selected and randomly divided into a study group and a control group according to the digital table method with 42 patients in each group. The study group was treated with tegafur plus cisplatin,and the control group was treated with 5-fluorouracil plus cisplatin.The treatment efficacy was evaluated by response evaluation criteria in solid tumors( RECIST),and the therapeutic results were compared between the two groups. Results The overall effective rate was 78. 6%in the study group which was higher than that 64. 3% in the control group( P < 0. 05). The incidence of adverse reactions was 11. 9% in the study group which was significantly lower than 26. 2% of the control group( P < 0. 05). Conclusion Tegafur plus cisplatin has obvious efficacy for advanced gastric cancer,which reduces adverse reactions and promotes the stability of the disease with good safety.更多还原