【摘要】 目的探讨胃间质瘤患者内镜黏膜下剥离术(ESD)术后出血的危险因素。方法选取2015年1月至2018年12月间上海市复旦大学附属华山医院收治的98例胃间质瘤患者,采用Logistic多因素回归分析方法分析患者ESD术后出血的相关影响因素。结果 98例患者中,有3例(3. 1%)术后出血。出血组患者中高血压和透析比例明显高于无出血组,差异均有统计学意义(均P <0. 05)。出血组患者的平均手术时间长于无出血组患者,差异有统计学意义(P <0. 05)。Logistic多因素回归分析显示,透析和手术时间≥75min是ESD术后患者出血的独立影响因素,差异均有统计学意义(均P <0. 05)。结论胃间质瘤患者ESD术后出血的独立影响因素是采用透析治疗和手术时间≥75min。更多还原

【Abstract】 Objective To determine the risk factors for postoperative hemorrhage in patients undergoing endoscopic submucosal dissection( ESD) for gastric stromal tumors. Methods Ninety-eight patients with gastric stromal tumors who underwent ESD at Huashan Hospital Affiliated to Fudan University from January 2015 to December 2018 were enrolled. The clinical factors of postoperative bleeding after ESD were analyzed using multivariate Logistic analysis. Results Among the 98 patients,hemorrhage was found in three patients( 3. 1%). Hypertension and dialysis rates were higher in patients with hemorrhage than patients without hemorrhage( all P < 0. 05). The average operation time was longer in patients with hemorrhage than in patients without hemorrhage( P < 0. 05). Multivariate Logistic regression analysis showed that dialysis and operative time ≥ 75 minutes was an independent risk factor for postoperative ESD bleeding( P <0. 05). Conclusion Dialysis operative time ≥ 75 min were independent risk factor for postoperative bleeding in patients undergoing ESD for gastric stromal tumors.更多还原