【摘要】 目的:探讨经桡动脉介入治疗术后发生桡动脉急性闭塞的危险因素。方法:连续入选我院2017年6月至2018年5月经桡动脉入路进行经皮冠状动脉造影或者介入治疗的患者845例,根据是否发生桡动脉急性闭塞,分为桡动脉闭塞组(n=46)和非桡动脉闭塞组(n=799)。采集患者临床资料并进行统计学分析。结果:桡动脉急性闭塞发生率为5.4%(46/845)。桡动脉闭塞组患者的年龄及女性、高血压、糖尿病及高甘油三酯血症的患者比例均高于非桡动脉闭塞组(P均<0.05);桡动脉闭塞组的术后桡动脉置管时间较非桡动脉闭塞组明显延长[41.1(25.5,60.8) h vs 19.9(10.3,26.6) h,P<0.05)。多因素Logistic分析显示,年龄>60岁(OR=4.415,95%CI:2.718～7.172,P<0.001)、桡动脉穿刺置管时间> 20 h(OR=3.078,95%CI:2.332～4.064,P<0.001)、糖尿病(OR=2.855,95%CI:1.286～6.336,P=0.010)为桡动脉闭塞独立危险因素。结论:高龄、糖尿病患者、穿刺置管时间过长均易造成桡动脉急性闭塞,是发生桡动脉闭塞的预测因素。更多还原

【Abstract】 Objectives: To define the risk factors of radial artery occlusion after transradial coronary interventions.Methods: Patients who underwent the transradial coronary interventions from June 2017 to May 2018 were included in this study. Patients were divided into radial artery occlusion group and non-radial artery occlusion group.Results: There were 46 patients in the radial artery occlusion group and 799 patients in the non-radial artery occlusion group. Results showed that prevalence of patients aged over 60 years old, female gender, hypertension, diabetes, and hypertriglyceridemia was significantly higher in the radial artery occlusion group and non-radial artery occlusion group(all P<0.05). Moreover, retention time of radial artery sheath post procedure was significantly longer in the radial artery occlusion group and non-radial artery occlusion(41.1[25.5, 60.8] h vs 19.9[10.3, 26.6] h, P<0.05). Multiple Logistic analysis showed that age>60 years old(OR=4.415, 95%CI: 2.718-7.172, P<0.001), retention time of radial artery sheath post procedure>20 h(OR=3.078, 95%CI: 2.332-4.064, P<0.001), diabetes(OR=2.855, 95%CI: 1.286-6.336, P=0.010) were the independent risk factors of the radial artery occlusion.Conclusions: Old age, diabetes and longer retention of radial artery sheath post procedure are risk factors of acute radial artery occlusion in this patient cohort.更多还原