【摘要】 目的:分析上海市2002—2013年唾液腺恶性肿瘤的人群发病状况,阐明疾病在本地区的流行病学特点。方法:根据上海市疾病预防控制中心提供的唾液腺恶性肿瘤病例资料,通过数据重新核实,采用SPSS 17.0软件包统计唾液腺恶性肿瘤的发病率、性别比、年龄分布状况、解剖部位占比以及病理分布情况;采用年均变化百分比、χ2检验和Fisher精确检验,比较年度之间的变化情况。结果:2002—2013年,上海市共诊断唾液腺恶性肿瘤新发病例2 308例,发病粗率为13.93/100万,标率为8.54/100万,性别比为1.08∶1;中位首诊年龄为58岁。12年间,发病率变化平稳。唾液腺恶性肿瘤中,1/3来自小唾液腺,其中1/3来自腭腺;大唾液腺的发病比为12∶3∶1。黏液表皮样癌、腺样囊性癌和非特异性腺癌是最常见的3大病理类型。结论:目前上海市唾液腺恶性肿瘤的发病率较低,但不同部位、不同病理类型的好发人群差异较大,提示发病危险因素存在差异,值得关注。更多还原

【Abstract】 PURPOSE: To analyze the incidence of salivary gland carcinoma in Shanghai from 2002 to 2013; And to clarify its epidemiological features. METHODS: The incidence data was retrieved from Shanghai Municipal Center for Disease Control & Prevention and re-checked before analysis. SPSS 17.0 software package was used to calculate the incidence rate, male/female ratio, age distribution, percentage of anatomic sites and demographic features of pathology.Comparisons of annual change were performed by annual percent change, Chi-square test and Fisher’s exact test.RESULTS: A total of 2 308 cases were newly diagnosed of salivary gland carcinoma from 2002 to 2013 in Shanghai. The crude incidence rate was 13.93 per 1 000 000 and the age-adjusted incidence was 8.54 per 1 000 000. The male to female ratio was 1.08 with median age of 58 years old. The annual incidence was stable during the study period. Among the total cases, one third occurred in minor salivary gland with palate being the most common origin. Carcinoma from major salivary gland confirmed the 12∶3∶1 distribution. Mucoepidermoid, adenoid cystic carcinoma and adenocarcinoma NOS were the top three pathological types. CONCLUSIONS: The incidence of salivary gland carcinoma was relatively low in Shanghai.However, the demography of different pathologic types or anatomic sites varied widely, indicating different risk factors for these cancers which deserves more attention.更多还原