【摘要】 目的比较泵前存在负压的条件下不同血液透析管路的实际流速。方法选取4种不同品牌的管路A、B、C、D,分别以200ml/min和300ml/min的设定流速运转5min,测量不同泵前负压条件下各管路的实际流速。结果①血泵设定流速相同时,泵前负压越大实际流速越低;②设定转速为200ml/min时,-120mmHg(1mmHg=0.133kpa)条件下不同品牌管路的实际流速无统计学差异(F=2.095,P=0.120),-100mmHg和-200mmHg条件下不同品牌管路的实际流速存在统计学差异(F=4.157,11.128,P=0.014,<0.001);③设定转速为300ml/min时,-100mmHg和-200mmHg条件下不同品牌管路的实际流速存在统计学差异(F=6.861,18.748,P=0.001,<0.001)。结论泵前负压影响体外循环的实际流速,且不同品牌的管路在相同负压条件下实际流速有一定差异,可进一步研究该差异对临床治疗效果的影响。更多还原

【Abstract】 Objective To compare the flow rate in bloodlines of different dialyzer under negative pressure. Methods In this paper, bloodlines A, B, C and D in 4 brands of dialyzers were selected. Each bloodline ran at the speed of 200 ml/min and 300 ml/min for 5 minutes, and the actual flow rate in each bloodline was measured under different pre-pump negative pressures. Results ①The greater the pre-pump negative pressure was, the lower the actual flow rate became under the same rate setting. ②There was no statistical difference in actual flow rate in different brands of bloodlines under the set conditions of flow rate 200 ml/min and the pressure-20 mmHg(F=2.095, P=0.120). In contrast, there was statistical difference in actual flow rate in the bloodlines under the pressure of-100 mmHg and-200 mmHg(F=4.157 and 11.128 respectively; P=0.014 and <0.001 respectively). ③There was statistical difference in actual flow rate in different brands of bloodlines under the rate of 300 ml/min and the pressure of-100 mmHg and-200 mmHg(F=6.861 and 18.748 respectively; P=0.001 and <0.001 respectively). Conclusion The negative pre-pump pressure affected the actual flow rate of extracorporeal circulation. The difference of actual flow rate existed among bloodlines of different brands under the same negative pressure conditions. Therefore, the clinical effect of these differences should be further studied.更多还原