【摘要】 目的研究东北铁线莲Clematis manshurica的化学成分。方法采用硅胶柱色谱、凝胶色谱及高压制备色谱等方法对东北铁线莲的三萜皂苷类成分进行分离纯化,并通过其理化性质及波谱数据对分离得到的化合物进行结构表征。结果从东北铁线莲中共分离得到10个齐墩果烷型三萜皂苷类化合物,分别鉴定为威灵仙皂苷L(1)、clematichinenosideA(2)、clematochinenoside F(3)、clematernoside A(4)、clematichinenoside B(5)、clematichinenoside C(6)、clematomandshurica saponin B(7)、clematomandshurica saponin D(8)、clematomandshurica saponin C(9)、huzhangoside B(10)。结论化合物1为新的三萜皂苷类化合物,2～6为首次从该植物中分离得到。更多还原

【Abstract】 Objective To study the chemical constituents from the roots of Clematis manshurica. Methods Ten compounds were separated and purified by silica gel, Sephadex LH-20, and preparative HPLC. The structures were identified by physicochemical properties and spectral analyses. Results A total of ten oleanane-type triterpenoid saponins were isolated and identified as clematomandshurica saponin L(1), clematichinenoside A(2), clematochinenoside F(3), clematernoside A(4), clematichinenoside B(5), clematichinenoside C(6), clematomandshurica saponin B(7), clematomandshurica saponin D(8), clematomandshurica saponin C(9), and huzhangoside B(10), respectively. Conclusion Compound 1 is a new oleanane-type triterpenoid glycoside, and compounds 2—6 are isolated from this plant for the first time.更多还原