【摘要】 目的研究鲁桑Morus multicaulis枝中的化学成分。方法采用多种色谱技术进行分离纯化,通过理化性质和波谱学数据对其进行结构鉴定。结果从鲁桑枝90%乙醇提取物中得到6个黄酮类成分,分别鉴定为桑枝酮A(1)、carpachromene(2)、补骨脂乙素(3)、异甘草素(4)、芹菜素(5)和槲皮素(6),其中化合物1的绝对构型通过圆二色谱量子化学计算得到了确定。结论化合物1为新化合物,命名为桑枝酮A,化合物2～4为首次从该植物中分离得到。更多还原

【Abstract】 Objective To investigate the chemical compounds from the twigs of Morus multicaulis. Methods The chemical constituents were isolated by various chromatographic methods from 90% ethanol aqueous extract of M. multicaulis and the structures were elucidated by a combined analysis of physicochemical properties, as well as spectroscopic methods including UV, IR, MS ECD and NMR. Results Six flavonoids were isolated and the structures were identified as moritwigsone A(1), carpachromene(2), isobavachalcone(3), isoliquiritigenin(4), apigenin(5), and quercitrin(6). The absolute configuration of compound 1 was determined by electronic circular dichroism(ECD) calculation. Conclusion Compound 1 is a new compound, named moritwigsone A, and compounds 2—4 are isolated from this plant for the first time.更多还原