【摘要】 患者男,51岁。右下肢暗紫红色皮疹半年余。患者近2个月反复出现口腔溃疡,尿常规检查结果示:潜血(+)。皮损组织病理示:表皮大致正常,真皮全层及皮下脂肪间隔可见以血管为中心的肉芽肿性改变,中央为变性坏死的血管,周围可见大量组织细胞、浆细胞及少量淋巴细胞浸润,并可见多核巨细胞。结合临床、尿常规及组织病理检查诊断为:Wegener肉芽肿。更多还原

【Abstract】 A 51-year-old male presented with purple-red rash on his right lower extremity for more than half a year.He had recurrent oral ulcer in recent two months,and with urine occult blood(+).The histopathological examination showed that the epidermis was generally normal,and there were granulomatous changes around blood vessels in the whole dermis and subcutaneous fat septum:blood vessels with degeneration and necrosis with a large number of tissue cells,plasma cells and a small number of lymphocytes,multicellular giant cells were also seen.Combined with clinical,urine routine and histopathological examination,the diagnosis of Wegener′s granulomatosis was made.更多还原