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瘤型麻风误诊1例分析

Analysis of a Case of Misdiagnosed Lepromatous Leprosy

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【作者】 吕超胡小平于波叶庭路

【Author】 LYU Chao;HU Xiaoping;YU Bo;YE Tinglu;Department of Dermatology,Clinical Institute of Peking University Shenzhen Hospital,Anhui Medical University;Department of Dermatology,Clinical Institute of Peking University Shenzhen Hospital;

【通讯作者】 胡小平;

【机构】 安徽医科大学北京大学深圳医院临床学院皮肤科北京大学深圳医院皮肤科

【摘要】 患者男,38岁。全身反复出现暗红斑3年,伴眉毛脱落、面部数个黄豆大肤色结节3个月余。多次予以抗过敏治疗,红斑可暂时减少,但反复发作。皮损组织病理示:真皮层见大量组织细胞,巢团状,弥漫分布,淋巴细胞少见,组织细胞胞浆空泡状,内见细短杆状的可疑微生物样结构;抗酸染色检查(+)。皮肤组织液查菌结果(2+~5+)。细菌密度指数(BI)4.2。诊断:瘤型麻风。

【Abstract】 A 38-year-old male presented with recurrent erythema all over the body for three years.He had partial eyebrow hair loss and several soybean-sized nodules on his face for more than three months.After repeated anti-allergy treatment,erythema was temporarily reduced,however,there was repeated attack.Histopathology showed that abundant histocytes in the dermis with nest-like structure,which were diffusely distributed.In addition,lymphocytes were rare,and intracytoplasmic vacuoles were seen in histocytes,with suspicious short-rod-shaped microbial structure.Acid-fast staining assay showed positive results.The result of bacteria detection of skin tissue fluid was 2+ ~ 5+.The bacterial density index(BI) was 4.2.The final diagnosis was lepromatous leprosy(LL).

【关键词】 瘤型麻风麻风过敏荨麻疹
【Key words】 Lepromatous leprosy(LL)LeprosyAllergyUrticaria
【基金】 深圳市三名工程项目资助(SZSM 201812059)
  • 【文献出处】 中国皮肤性病学杂志 ,The Chinese Journal of Dermatovenereology , 编辑部邮箱 ,2019年07期
  • 【分类号】R755.2
  • 【被引频次】1
  • 【下载频次】109
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