【摘要】 目的探讨天疱疮的临床特点、治疗方法和预后。方法对2007年1月-2016年8月收集的118例天疱疮患者的临床资料进行回顾性分析。结果轻症患者需要的激素控制量为(0.90±0.42) mg/(kg·d),中症患者需要的激素控制量为(1.16±0.40) mg/(kg·d),重症患者需要的激素控制量为(1.24±0.60)mg/(kg·d)。三者之间差异有统计学意义(P=0.005)。结论天疱疮好发于中年人,其严重程度决定激素的用量及预后。糖皮质激素是目前治疗天疱疮的首选药物。更多还原

【Abstract】 Objective To analyze the clinical features, therapeutic efficacy and the prognosis of pemphigus. Methods The clinical data from 118 hospitalized patients with different types of pemphigus were retrospectively analyzed from January 2007 to August 2016. Results The dose of glucocorticoid in severe cases prednisone(1.24±0.60) mg/(kg·d),which was used to alleviate lesions,was much more higher than that in mild cases(0.90±0.42) mg/(kg·d) or moderate cases(1.16±0.40) mg/(kg·d)(P=0.005).Conclusion Pemphigus occurred predominantly in the middle-aged patients. The severity of pemphigus is a key factor of determining the dosage of corticosteroid. Presently glucocorticoid is still a main treatment for pemphigus.更多还原