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醒脑静联合盐酸纳洛酮治疗脑出血后昏迷患者的疗效分析
Therapeutic Effect of Xingnaojing Combined with Naloxone Hydrochloride on Patients with Coma after Cerebral Hemorrhage
【摘要】 目的分析醒脑静联合盐酸纳洛酮治疗脑出血后昏迷患者治疗效果。方法选取我院2015年1月~2017年10月中收治脑出血后昏迷患者68例作为研究对象,随机分为参照组和联合组,每组34例。参照组在常规治疗上加盐酸纳洛酮,联合组在参照组的基础上加用醒脑静配合治疗,将两组GCS分值与脑血肿量变化及NIHSS评分情况进行比较。结果治疗后联合组的GCS分值(14.24±2.05)分与脑血肿量(17.41±2.44)ml明显优于参照组的(9.87±1.62)分和(25.50±2.42)ml,差异有统计学意义(P<0.05);联合组在出院后3个月的NIHSS评分情况(10.01±1.95)分优于参照组(12.50±2.31)分,差异有统计学意义(P<0.05)。结论采用醒脑静联合盐酸纳洛酮治疗脑出血后昏迷患者可显著改善脑出血患者的意识障碍,促进神经功能恢复,减轻脑部水肿情况,改善患者临床疗效。
【Abstract】 Objective To analyze the therapeutic effect of Xingnaojing combined with naloxone hydrochloride in the treatment of coma patients with cerebral hemorrhage. Methods A total of 68 patients with coma after cerebral hemorrhage were enrolled in our hospital from January 2015 to October2017. They were randomly divided into reference group and combined group, with 34 cases in each group. In the reference group, naloxone hydrochloride was added to the conventional treatment, and the combined group was treated with Xingnaojing on the basis of the reference group. The GCS scores of the two groups were compared with the changes of cerebral hematoma volume and NIHSS score. Results After treatment, the GCS score(14.24±2.05) and cerebral hematoma volume(17.41±2.44) ml were significantly better than the reference group(9.87±1.62) and(25.50±2.42) ml,the difference was statistically significant(P<0.05); The NIHSS score(10.01±1.95) in the combined group was better than the reference group(12.50±2.31) at 3 months after discharge,the difference was statistically significant(P<0.05). Conclusion The treatment of coma after cerebral hemorrhage with Xingnaojing combined with naloxone hydrochloride can significantly improve the disturbance of consciousness in patients with cerebral hemorrhage, promote the recovery of nerve function, reduce the edema of the brain and improve the clinical efficacy of patients.
【Key words】 Xingnaojing; Naloxone hydrochloride; Coma after cerebral hemorrhage;
- 【文献出处】 医学信息 ,Medical Information , 编辑部邮箱 ,2019年06期
- 【分类号】R743.34
- 【被引频次】6
- 【下载频次】53