【摘要】 目的探讨多种药物联合治疗白内障术后干眼症的临床疗效。方法选取2015年5月～2018年9月于我院行白内障手术术后干眼患者125例,随机分为A、B、C组三组,C组患者采用玻璃酸钠滴眼液治疗,A组在C组基础上加用贝复舒滴眼液治疗,B组在C组基础上加用普拉洛芬滴眼液治疗,比较各组患者治疗前后OSDI值、BUT、SIt值、FL的变化,比较各组患者治疗前后OSDI值、BUT、SIt值、FL的变化。结果治疗后三组患者BUT,SIt值比较,差异有统计学意义(P<0.05);治疗后三组OSDI值,FL比较,差异无统计学意义(P>0.05);B组患者治疗的总有效率(95.24%)高于A组(93.02%)及C组(87.50%),差异有统计学意义(P<0.05)。结论玻璃酸钠滴眼液联合普拉洛芬滴眼液、玻璃酸钠滴眼液联合贝复舒滴眼液及单纯使用玻璃酸钠滴眼液均可减轻白内障术后干眼症患者的症状,增加泪液分泌量,延长泪膜破裂时间,使角膜染色降低,但玻璃酸钠滴眼液联合普拉洛芬滴眼液的治疗方案更佳。更多还原

【Abstract】 Objective To investigate the clinical efficacy of multiple drugs in the treatment of xerophthalmiaafter cataract surgery. Methods A total of125 patients with xerophthalmia who underwent cataract surgery in our hospital from May 2015 to September 2018 were randomly divided into three groups: group A, group B and group C. Patients in group C were treated with sodium hyaluronate eye drops. Group A was treated with Beifushu eye drops on the basis of group C. Group B was treated with pranoprofen eye drops on the basis of group C.The changes of OSDI, BUT, SIt and FL before and after treatment were compared between the groups. Results After treatment, the BUT and SIt values of the three groups were significantly different(P<0.05). There were no significant differences in the OSDI values and FL between the three groups after treatment( P>0.05). The effective rate(95.24%) was higher than that of group A(93.02%) and group C(87.50%),the difference was statistically significant( P<0.05). Conclusion Sodium hyaluronate eye drops combined with pranoprofen eye drops, sodium hyaluronate eye drops combined with Beifushu eye drops and sodium hyaluronate eye drops alone can alleviate the symptoms of xerophthalmia patients after cataract surgery. Increase the amount of tear secretion, prolong the tear film rupture time, and reduce the cornea staining, but the treatment plan of sodium hyaluronate eye drops combined with pranoprofen eye drops is better.更多还原