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基于真实世界的注射用丹参多酚酸临床用药合理性分析

Based on real world:rational analysis of clinical use of Salvianolic Acid for Injection

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【作者】 于倩王华谢程

【Author】 YU Qian;WANG Hua;XIE Cheng;Department of Pharmacy,China-Japan Union Hospital of Jilin University;

【通讯作者】 谢程;

【机构】 吉林大学中日联谊医院药学部

【摘要】 目的了解注射用丹参多酚酸临床应用情况,为临床合理用药提供参考。方法采用医院集中监测方法选取吉林大学中日联谊医院2018年8月—2019年4月使用注射用丹参多酚酸的住院患者,从用药科室、适应症、疗程、给药剂量、溶媒种类、溶媒体积、给药频次、滴速、是否冲管、合并用药等方面进行统计分析。结果2 000例用药者中适应症不适宜占20.25%,选用溶媒不适宜占0.2%,溶媒体积不适宜占0.05%,疗程不足占96.3%,超疗程用药占1.35%,未标注滴速占29.35%,未冲管占29.95%,合并用药占47.95%,交替用药占36.8%,重复用药占1.85%,不良反应发生率为0.2%。结论注射用丹参多酚酸安全性良好,临床使用中存在疗程不足及超适应症用药现象,应加强管理。

【Abstract】 Objective To understand the clinical application of Salvianolic Acid for Injection,and provide reference for clinical rational use.Methods The hospital centralized monitoring method was used to select inpatients who used Salvianolic Acid for Injection from August 2018 to April 2019 in China-Japan Union Hospital of Jilin University.Statistical analysis was performed from the medication department,indications,course of treatment,dose of administration,types and volume of solvent media,frequency of administration,dropping speed,flushing,combined medication,etc.Results In 2 000 cases,the indication was not suitable for20.25%,the solvent was not suitable for 0.2%,the dissolution media was not suitable for 0.05%,the treatment was insufficient for96.3%,the overdose of course of treatment was 1.35%,the unlabeled dropping rate was 29.35%,and the untreated tube was 29.95%.The combined medication was 47.95%,the alternating medication was 36.8%,the repeated medication was 1.85%,and the incidence of adverse reactions was 0.2%.Conclusion The safety of Salvianolic Acid for Injection is good,and there are insufficient treatment courses and over-indications in clinical use,and management should be strengthened.

  • 【文献出处】 药物评价研究 ,Drug Evaluation Research , 编辑部邮箱 ,2019年11期
  • 【分类号】R969.3
  • 【被引频次】3
  • 【下载频次】209
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