【摘要】 目的研究注射用丹参多酚酸对急性缺血性脑卒中的临床疗效。方法选取急性缺血性脑卒中患者200例,随机分为观察组和对照组,各100例。纳入研究的200例患者均给予常规抗凝[阿司匹林(100～300)mg/d]、降脂(阿托伐他汀20 mg/d)及非丹参类中成药进行治疗,观察组在此基础上再给予注射用丹参多酚酸100 mg/d静脉滴注。两组均以14 d为1个疗程,评价患者的临床疗效、神经功能缺损情况(NIHSS评分)、日常生活能力(ADL评分)。结果观察组总有效率为91%,显著高于对照组的75%(P<0.05)。两组治疗前后比较,NIHSS评分明显降低,ADL评分明显升高,差异具有统计学意义(P<0.05);治疗后观察组的NIHSS评分和ADL评分改善程度显著优于对照组(P<0.05)。结论注射用丹参多酚酸对急性缺血性脑卒中神经功能的恢复有一定的促进作用。更多还原

【Abstract】 Objective To study the clinical effect of Salvianolic Acids for Injection on acute ischemic stroke. Methods Tatolly 200 patients with acute ischemic stroke were randomly divided into observation and control group. The patients in control group were treated with routine medical treatment, while those in observation group were treated with Salvianolic Acids for Injection on the basis of routine treatment. The clinical curative effect, neurological deficit(NIHSS score) and activities of daily living(ADL) of the patients in both groups were observed after 14 days as a course of treatment. Results The total effective rate of observation group was 91%, and the total effective rate was significantly higher than that in the control group(75%)(P < 0.05). After treatment, the improvement of neurological deficit and Barthel index in observation group were significantly better than that in control group(P <0 05). Conclusion Salvianolic Acids for Injection can promote the recovery of neurological function in acute ischemic stroke.更多还原