【摘要】 空腹血糖(fasting plasma glucose,FPG)不仅是糖化血红蛋白水平的关键决定因素,也是餐后血糖及血糖波动的直接影响因素,FPG达标是2型糖尿病患者治疗的重要目标。血糖达标需根据患者自身血糖特点,制定个体化目标,采取个体化方案,并适时起始个体化胰岛素治疗。本文将通过系统回顾循证证据,解析FPG对糖尿病治疗之重要意义,并探讨基础胰岛素,尤其是新型基础胰岛素类似物在FPG控制方面的重要作用。更多还原

【Abstract】 Fasting plasma glucose(FPG) is not only a key determinant of glycosylated hemoglobin, but also a direct influencing factor of postprandial plasma glucose and blood glucose fluctuations. Keeping FPG under control is an important target for the treatment of type 2 diabetes. The goal of blood glucose should be achieved on the basis of the patient’s own characteristics of blood glucose. We need to set up an individualized goal, adopt individualized regimens and initiate individualized insulin therapy at the appropriate time. In this paper, we will systematically review the evidencebased data to understand the importance of FPG for the treatment of diabetes, and to explore the important role of basal insulin, especially the novel basal insulin analogues, in the controlling of FPG.更多还原