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肺泡灌洗液检出多量泡沫样细胞4例报道

Detection of a large amount of foamy cells in bronchial alveolar lavage fluid: a report of 4 cases

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【作者】 李文娟黄祥奇周宇麒张天托

【Author】 Li Wenjuan;Huang Xiangqi;Zhou Yuqi;Zhang Tiantuo;Department of Respiratory, the Third Affiliated Hospital of Sun Yat-sen University;

【通讯作者】 张天托;

【机构】 中山大学附属第三医院呼吸内科中山大学附属第三医院病理科

【摘要】 肺泡灌洗液(BAL)在肺部相关疾病的诊断中有着重要的临床意义,BAL检出特征性多量泡沫样细胞十分罕见。该文报道了4例BAL中检出大量泡沫样细胞的临床病例,4例患者分别确诊为肺腺癌合并鞭虫感染、肺腺癌、肺隐球菌感染、SLE合并抗磷脂抗体综合征及肺栓塞。该4例的诊治经过提示,如BAL检出大量泡沫样细胞,临床可迅速缩小诊断思考范围,可通过完善风湿免疫相关检查、肺部CT增强扫描、隐球菌抗原或寄生虫相关检查、肿瘤相关筛查、询问既往可疑药物及生活环境暴露史等进一步明确诊断。

【Abstract】 Bronchial alveolar lavage fluid(BAL) plays a pivotal role in the diagnosis of lung diseases. Detection of a large amount of characteristic foamy cells in BAL is rarely encountered. In this article, a large quantity of foamy cells was detected in the BAL of 4 cases. They were diagnosed with pulmonary adenocarcinoma combined with Trichinella infection, pulmonary adenocarcinoma, pulmonary cryptococcal infection, SLE with antiphospholipid antibody syndrome and pulmonary embolism. The diagnosis and treatment of these patients prompted that the range of clinical diagnosis could be rapidly narrowed if a massive amount of foamy cells was detected in the BAL. Moreover, the diagnosis can be confirmed by complete rheumatism immunity-related examination, enhanced CT scan of the lung, Cryptococcus antigen or parasite-related examination, tumor screening, inquiry of medical history of drug use and environmental exposure, etc.

【关键词】 肺泡灌洗泡沫样细胞诊断
【Key words】 Bronchial alveolar lavageFoamy cellDagnosis
【基金】 国家自然科学基金(81370114)
  • 【文献出处】 新医学 ,Journal of New Medicine , 编辑部邮箱 ,2019年09期
  • 【分类号】R563
  • 【下载频次】61
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