【摘要】 目的探讨2型糖尿病患者下肢动脉超声结果与颈动脉超声结果的相关性,及两者与心脑血管疾病(CCVD)的相关性。方法选择338例2型糖尿病患者为研究对象,以问卷调查方式收集基本信息,并进行体格测量、生化检查和下肢动脉、颈动脉超声检查,对收集的信息进行横断面分析。结果 Gamma相关性分析显示,下肢动脉病变与颈动脉病变有关(Gamma=0.602,P <0.001)。Logistic回归显示,在校正年龄、病程、高血压病的影响后,颈动脉病变与CCVD相关(OR=2.58,95%CI 1.13～5.89,P <0.05),下肢动脉病变也与CCVD相关(OR=5.34,95%CI2.34～12.17,P <0.05)。结论 2型糖尿病患者下肢动脉病变与颈动脉病变有关,下肢动脉病变等级越高,颈动脉病变等级也越高,且两者均与CCVD的发生相关。更多还原

【Abstract】 Objective To investigate the correlation between the lower-extremity and carotid arterial ultrasound diseases(CCVD) in patients with type 2 diabetes mellitus. Methods A total of 338 patients with type 2 diabetes mellitus were recruited in this clinical trial. Baseline data were collected by questionnaire survey.Physical carotid arteries were conducted. The collected data were subject to cross-sectional analysis. Results Gamma correlation analysis showed a signi?cant association between the severity of lower-extremity and carotid arterial diseases(Gamma = 0.602, P < 0.001). Logistic regression analysis demonstrated that CCVD was signi?cantly associated with carotid arterial disease(OR = 2.58, 95%CI 1.13-5.89, P < 0.05) and lower-extremity arterial disease(OR = 5.34, 95%CI 2.34-12.17, P < 0.05) after adjusting the effects of age, course of disease and hypertension. Conclusions The lower-extremity arterial disease is correlated with the carotid arterial disease in type 2 diabetes mellitus patients. The higher grade of the lower-extremity arterial disease, the higher grade of carotid arterial disease. Lower-extremity arterial diseases and carotid arterial diseases are both correlated with the incidence of CCVD.更多还原