【摘要】 目的探讨微创拔牙术对下颌低位阻生智齿的疗效及血清抗牙龈叶琳菌抗体(PgIgG)、肿瘤坏死因子-α(TNF-α)、白介素-6(IL-6)的影响。方法选取2015年11月～2017年11月商洛市中心医院就诊的93例下颌低位阻生智齿的患者为研究对象,按照随机数表法分为观察组(n=47)和对照组(n=46),观察组给予微创拔牙术治疗,对照组使用锤凿劈冠法治疗。比较两组手术情况,血清抗PgIgG、TNF-α、IL-6,视觉模拟评分法(VAS)、牙槽骨密度及并发症。结果观察组手术时间明显短于对照组,且术中出血量明显少于对照组(均P<0.05);术后,两组血清抗PgIgG、TNF-α、IL-6均明显高于术前(均P<0.05),但观察组血清抗PgIgG、TNF-α、IL-6均明显较对照组低(均P<0.05);观察组在手术后1、3、7d时,VAS评分明显低于对照组(均P<0.05);观察组术后7、30d时牙槽骨密度明显高于对照组(均P<0.05);观察组根折、邻牙松动、术后张口受限、面颊肿胀、感染、干槽症的总发生率(12.77%)明显低于对照组(30.43%)(P<0.05)。结论对下颌低位阻生智齿患者使用微创拔牙术效果显著,术后血清抗PgIgG、TNF-α、IL-6表达低,对患者创伤小,有利于减少术后并发症,促进恢复,临床应用价值较高。更多还原

【Abstract】 Objective To study the curative efficacy of minimally invasive extraction in treatment of mandibular impacted wisdom tooth and its effects on serum anti gingival leaf bacteria antibody(PgIgG),tumor necrosis factor-α(TNF-α)and interleukin-6(IL-6)levels.Methods 93 patients of mandibular impacted wisdom tooth received therapy from November 2015 to November 2017 in Shangluo Central hospital were selected as research objects.According to random number table,those patients were divided into the observation group and the control group.The observation group was treated with minimally invasive extraction,while the control group was treated with hammer chop and split crown.The operation conditions,serum anti-PgIgG,TNFa,IL-6,visual analogue score(VAS),alveolar bone density and complications were compared between the two groups.Results The operative time in the observation group was significantly shorter than those in the control group,and the intraoperative blood loss was significantly less than those in the control group(P<0.05).After operation,the serum anti-PgIgG,TNF-a,IL-6 in the two groups were significantly higher than those before operation(P<0.05),but the serum anti-PgIgG,TNF-a,IL-6 in the observation group were significantly lower than those in the control group(P<0.05).The VAS scores in the observation group were significantly lower than those in the control group at after operation1 d,3 dand 7 d(P<0.05).The alveolar bone density in the observation group was significantly higher than those in the control group at after operation7 dand 30 d(P<0.05).The total incidence of root fracture,abutment loosening,postoperative restriction of mouth opening,cheek swollen,infected and alveolalgia in the observation group was 12.77%,which was significantly lower than those in the control group 30.43%(P<0.05).Conclusion Minimally invasive extraction is well for mandibular impacted wisdom tooth.The serum anti PgIgG,TNF-αand IL-6 were low after operation,and the wound was small.It’s helpful to reduce postoperative complications,promote postoperative recovery,and has high clinical application value.更多还原