【摘要】 目的探讨胺碘酮对抢救心力衰竭伴快速心房颤动患者治疗效果的影响。方法以2018年1月-2019年1月在我院接受救治的心力衰竭伴快速心房颤动患者96例为研究对象,结合患者入院时间先后分为两组,且两组患者分别在常规治疗基础上给予地高辛治疗(对照组48例)及胺碘酮治疗(观察组48例),观察两组患者治疗效果及不良反应情况,测定两组患者房颤转复时间及用药前、用药30 min后、用药24 h后心室率差异,同时统计两组患者治疗前后左室舒张末期容积、左室射血分数、左室收缩末期容积等心功能指标差异。结果观察组临床疗效优于对照组(P<0.05);观察组患者房颤转复时间较对照组明显缩短(P<0.05);治疗前两组患者心室率比较差异无统计学意义(P>0.05);用药30 min、2 h、24 h后,观察组与对照组患者的心室率均较治疗前明显降低,且观察组下降幅度大于对照组(P<0.05)。结论在抢救心力衰竭合并快速心房颤动患者的过程中,胺碘酮的应用可有效改善临床疗效,安全,可有效控制心力衰竭合并快速心房颤动心室率,使部分患者房颤转复,临床价值显著,值得关注。更多还原

【Abstract】 Objective To investigate the effect of amiodarone on the treatment of patients with heart failure and rapid atrial fibrillation. Methods From January 2018 to January 2019 in our hospital, 96 heart failure patients with rapid atrial fibrillation were enrolled in the study. According to the admission time, the patients were divided into two groups, 48 cases in each group. The patients in the control group recieves conventional treatment and those in the observation group accepted amiodarone treatment. The clinical efficacy were observed in the two groups and the adverse reactions were measured in patients with atrial fibrillation. The recovery time, left ventricular end-diastolic volume(LVED), left ventricular ejection fraction(LVED) and left ventricular end-systolic volume(LVESV) were measured before and after treatment in the two groups. Results There was no significant difference in the ventricular rate between the two groups before treatment(P>0.05). The difference of the two groups was not statistically significant(P>0.05); The clinical effect of the observation group was significantly higher than that of the control group(P>0.05). The ventricular rate of the observation group was significantly lower than that of the control group at 30 min, 2 h and 24 h(P<0.05). Conclusion Amiodarone can effectively improve the clinical curative effect and safety in patients with heart failure complicated with rapid atrial fibrillation. It can effectively control the ventricular rate of heart failure with rapid atrial fibrillation and make some patients recover from atrial fibrillation.更多还原