【摘要】 目的研究肺部感染患者常见耐药菌的耐药性,为临床提供参考。方法对ICU肺部感染患者297株多重耐药菌资料进行回顾性分析。结果检出的前5种多重耐药菌为鲍曼不动杆菌、肺炎克雷伯菌、大肠埃希菌、铜绿假单胞菌及金黄色葡萄球菌。鲍曼不动杆菌对阿米卡星较敏感,对其他检测药物均出现较高的耐药率;肺炎克雷伯菌对阿米卡星及美罗培南较敏感;金黄色葡萄球菌对利奈唑胺、万古霉素及替加环素保持较高的敏感性;大肠埃希菌对阿米卡星及哌拉西林/他唑巴坦保持较低耐药率。铜绿假单胞菌对阿米卡星较敏感。结论 ICU肺部感染多重耐药菌对抗生素耐药严重,应加强细菌的耐药性监测,有效控制多重耐药菌的感染。更多还原

【Abstract】 Objective To study the drug resistance of common drug-resistant bacteria in patients with pulmonary infection and provide a reference for clinical practice. Methods Retrospective analysis was performed on 297 strains of multidrug-resistant bacteria in patients with ICU pulmonary infection. Results The first 5 multidrug-resistant bacteria were acinetobacter baumannii, klebsiella pneumoniae, escherichia coli,pseudomonas aeruginosa and staphylococcus aureus. Acinetobacter baumannii is sensitive to amikacin and has high resistance rate to other tested drugs. Klebsiella pneumoniae is sensitive to amikacin and meropenem. Staphylococcus aureus was highly sensitive to linazolamide, vancomycin and tegacycline. Escherichia coli maintained a low resistance rate to amikacin and piperacillin/tazobactam.Pseudomonas aeruginosa is sensitive to amikacin. Conclusion In order to control infection effectively, early tracheal secretion culture should be carried out in time, improve the cure rate of patients.更多还原