【摘要】 心血管疾病(Cardiovascular diseases,CVD)是我国近年来发病率及死亡率逐渐增高的疾病,阿司匹林已被证明在预防和治疗CVD方面具有显著的临床效果,并且是全世界范围内使用最广泛的药物之一。大量研究表明,阿司匹林是心血管病二级预防的基石用药,若患者无服用阿司匹林的禁忌症或严重不良反应,应该坚持长期甚至终身的预防用药。但实际上,阿司匹林依从性并不是理想的,并且随意停用或不规律服用阿司匹林者,可能会诱导血栓形成,从而增加心血管不良事件发生的风险。本文主要概述在心血管疾病中,关于阿司匹林依从性重要性,依从性差的原因以及可用于提高阿司匹林药物依从性的策略,对于未来临床工作中应用阿司匹林,具有一定的指导意义。更多还原

【Abstract】 Cardiovascular disease(CVD) is a disease with increasing morbidity and mortality in recent years. Aspirin has been shown to have significant clinical effects in the prevention and treatment of CVD, and is one of the most widely used drugs worldwide. A large number of studies have shown that aspirin is the cornerstone of secondary prevention of cardiovascular disease. If patients do not take any contraindications or serious adverse reactions to aspirin, they should adhere to long-term or even lifelong preventive medication. In fact, aspirin compliance is not ideal, and random withdrawal or irregular administration of aspirin may induce thrombosis, which increases the risk of cardiovascular adverse events. This article outlines the importance of aspirin compliance, the reasons for poor adherence, and strategies that can be used to improve aspirin drug compliance in cardiovascular disease, which has certain guiding significance for the future application of aspirin in clinical work.更多还原