【摘要】 目的监测糖尿病患者活动性人巨细胞病毒(HCMV)感染,并探讨其临床意义。方法应用聚合酶链式反应(PCR)检测377例糖尿病患者尿液中HCMV-DNA阳性率。结果本研究中糖尿病患者的HCMV-DNA阳性率为15.9%,对照组阳性率为0.96%,两者相比差异具有统计学意义(P<0.01);不同年龄组HCMV活动性感染相比,发现发病年龄<30岁组的HCMV-DNA阳性检出率最高;从糖尿病患者病程来看,病程<1年组的HCMV-DNA阳性率明显高于其他年龄组。结论糖尿病患者易发生活动性的HCMV感染。更多还原

【Abstract】 The aim of this study is to monitor the active human cytomegalovirus(HCMV) infection suffered by diabetes patients and explore its effects on clinical practice accordingly. Polymerase chain reaction(PCR) was applied to determine the positive rate of HCMV-DNA in urine of 377 diabetes patients. The results of this study are as follows.Firstly, the positive rate of HCMV-DNA was 15.9% in diabetes patients, while it was 0.96% in control group. The difference is statistically significant(P< 0.01). Secondly, by comparing the active HCMV infection in different age groups, we found the positive rate of HCMV-DNA was the highest in the group with episode age less than 30. Thirdly,in terms of the course of diabetes patients, the positive rate of HCMV-DNA in the group with the course less than one year was significantly higher than that in other age groups. Thus it can be concluded that diabetes patients are prone to active HCMV infection.更多还原