【摘要】 粘附分子的表达和上调是炎症过程中介导白细胞的粘附、迁移募集及肉芽肿形成的基础,其选择素家族及其相应的配体在炎症细胞迁移的早期起着重要作用,同时它们也可作为共刺激信号调节T细胞增殖活化。结核感染时,其表达均有所升高;并且通过不同的方式在抗结核免疫的多个环节发挥作用,本文就不同粘附分子在结核感染中的表达作一综述如下。更多还原

【Abstract】 The expression and upregulation of adhesion molecules are the basis of leukocyte adhesion, migration, recruitment and granuloma formation. The selectin family and its corresponding ligand play an important role in the early stage of inflammatory cell migration. At the same time, they can also act as costimulatory signals to regulate the proliferation and activation of T cells. In this paper, the expression of different adhesion molecules in tuberculosis infection is summarized as follows.更多还原