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TFF3与胃癌标记物
TFF3 and Gastric Cancer Biomarker
【摘要】 TFF3是黏蛋白相关家族肽三叶因子家族(trefoil factor family, TFF)成员之一,主要由小肠和大肠杯状细胞分泌,正常胃黏膜中不表达或少量表达,在胃癌组织有特异性表达。TFF3可作为早期非侵入性诊断胃癌的潜在标记物,对胃癌的发生、发展具有提示作用,可用于胃癌的预后筛查。
【Abstract】 TFF3 is one member of trefoil factor family(TFF),which is related to the development of gastric cancer intently.It is secreted mainly by goblet cells in small and large intestine, and is not expressed or expressed in small amounts in normal gastric mucosa.TFF3 is highly sensitive and specific to the development of gastric cancer tissue. TFF3 had a special expression in the early gastric cancer, which can be used as a signaling molecule of early cancerization. It also has certain influence on the occurrence,development and prognosis of gastric cancer.
【基金】 山东省教育厅课题(项目编号:J15LK07);泰山医学院2016年国家大学生创新计划(项目编号:201610439041)
- 【文献出处】 世界最新医学信息文摘 ,World Latest Medicine Information , 编辑部邮箱 ,2019年28期
- 【分类号】R735.2
- 【被引频次】2
- 【下载频次】130