【摘要】 研究证据显示类风湿关节炎患者中结核发病风险较高,尤其是接受肿瘤坏死因子拮抗剂治疗后活动性结核感染风险明显增加,而治疗前进行规范化的结核筛查并予以预防性抗结核治疗可以降低活动性结核的风险。本文主要就肿瘤坏死因子拮抗剂致类风湿性关节炎患者结核病患病率增加的近期进展作一综述。更多还原

【Abstract】 Some research evidence shows that the risk of tuberculosis in patients with rheumatoid arthritis is high, especially in patients treated with tumor necrotizing factor inhibitor(TNFi). Screening and treatment of latent tuberculosis infection before the initiation of TNFi therapy can reduce the risk of active tuberculosis. This article reviews the recent advances in tuberculosis among rheumatoid arthritis patients treated with TNFi.更多还原