【摘要】 目的分析探讨心绞痛患者PCI术后心肌标记物升高的机制及临床意义。方法选取2016年1月至2017年8月我院收治的心绞痛患者180例,将所选患者随机平均分为三组,全部进行PCI手术治疗,手术结束4-24 h后,对第一组抽血查CK-MB,第二组抽血查肌钙蛋白,第三组抽血查超敏肌钙蛋白。检查结束后,分别对这三组心绞痛患者心肌标记物的升高率进行比较。对检出心肌标记物增高的这部分人群作为研究组,其余PCI术后心肌标记物正常的作为对照组,对两组心绞痛患者术后一年的随访时心脏不良事件发生率进行比较。结果研究组患者术后一年的心脏不良事件发生率显著高于对照组患者(P<0.05)。结论在治疗过程当中,对心绞痛患者PCI术后心肌标记物的检测,尤其是超敏肌钙蛋白测定,在PCI术后患者远期心脏不良事件的防治方面有显著作用,更好的指导PCI术后患者规范化治疗,降低患者不良反应的发生率,有助于改善患者的预后,可在临床上进行推广。更多还原

【Abstract】 Objective To analyze and investigate mechanism and clinical significance of myocardial markers elevation of angina pectoris patients after PCI. Methods Choose 180 cases angina pectoris patients treated in our hospital from January 2016 to August 2017, divide them into three groups in average randomly, all patients were treated with PCI surgery. 4-24 hours after operation, detect CK-MB by drawing blood in the first group, detect troponin in the second group and hypersensitive troponin in the third group. After detection, compare elevation rates of myocardial markers of three groups. Treat those with elevated myocardial markers as study group and those with normal myocardial markers as control group after PCI. Compare adverse cardiac events incidence during one-year followup of angina pectoris patients between two groups. Results Adverse cardiac events incidence in study group was significantly higher than control group one year after operation(P< 0.05). Conclusion During treatment, detection of myocardial markers after PCI of angina pectoris patients, especially determination of hypersensitive troponin, has significant role in prevention and treatment of long-term adverse cardiac events after PCI, which can better guide standardized treatment of patients after PCI, reduce adverse reactions incidence, help to improve prognosis of patients,and can be promoted in clinical practice.更多还原