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2型糖尿病患者血糖水平与颈动脉斑块性质的相关性

Correlation between Blood Glucose Level and Carotid Plaque Properties in Patients with Type 2 Diabetes

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【作者】 王占波王大伟韩广明乔建勇

【Author】 WANG Zhan-bo;WANG Da-wei;HAN Guang-ming;QIAO Jian-yong;Chengde Medical College;Chengde Central Hospital (Second Clinical College of Chengde Medical College);

【通讯作者】 乔建勇;

【机构】 承德医学院承德市中心医院(承德医学院第二临床学院)

【摘要】 目的探讨2型糖尿病患者血糖水平与颈动脉斑块性质的相关性。方法收集2016年1月~2017年12月就诊于我院经颈动脉超声检测确诊有颈动脉斑块形成患者274例,根据有无2型糖尿病分为糖尿病组182例和非糖尿病组92例,检测两组患者的空腹血糖、颈动脉内中膜厚度(IMT)及斑块性质、血压、TC、TG、HDL和LDL,并分析糖尿病组影响颈动脉斑块性质的因素。结果与非糖尿病组比较,糖尿病组不稳定斑块检出率较高(P<0.05)。Logistic回归分析显示,糖尿病组患者的性别、空腹血糖水平是颈动脉不稳定斑块的独立危险因素。结论2型糖尿病患者的空腹血糖水平影响颈动脉斑块的性质。

【Abstract】 Objective To investigate the relationship between blood glucose level and carotid plaque properties in patients with type 2 diabetes. Methods A total of 274 patients with carotid plaque formation diagnosed by carotid artery ultrasonography from January 2016 to December 2017 were enrolled. According to the presence or absence of type 2 diabetes, 182 patients were divided into diabetes group and 92 patients with non-diabetic group. Fasting blood glucose, carotid plaque thickness(IMT) and plaque properties, blood pressure, TC, TG, HDL and LDL were measured in the two groups, and the factors affecting the carotid plaque in the diabetic group were analyzed. Results Compared with the non-diabetic group, the detection rate of unstable plaque in the diabetic group was higher(P<0.05). Logistic regression analysis showed that gender and fasting blood glucose levels in the diabetic group were independent risk factors for unstable carotid plaque. Conclusion Fasting blood glucose levels in patients with type 2 diabetes affect the nature of carotid plaque.

【基金】 科技部国家科技支撑计划项目“缺血性脑血管病和脑肿瘤防治关键技术研究”(2015BAI12B04)
  • 【文献出处】 世界最新医学信息文摘 ,World Latest Medicine Information , 编辑部邮箱 ,2019年08期
  • 【分类号】R587.2
  • 【被引频次】3
  • 【下载频次】102
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