【摘要】 背景:功能性消化不良(FD)患者常合并焦虑状态或焦虑症,有效识别其危险因素有助于精准使用抗焦虑药物,改善患者的预后。目的:探讨FD患者合并焦虑症的临床特点和相关危险因素。方法:选取2014年6月—2014年9月中南大学湘雅二医院确诊的295例FD患者,行汉密尔顿焦虑量表评估FD患者的焦虑状态。分析FD合并焦虑症的危险因素。结果:FD患者中焦虑症的发病率为8. 1%(24/295),单因素分析显示年龄、病程、婚姻状况、既往精神病史、精神药物使用史与FD合并焦虑症有关(P <0. 05);多因素分析显示病程、婚姻状况和既往精神病史为FD并发焦虑症的危险因素(P <0. 05)。结论:病程长、婚姻不完整和既往精神病史为FD合并焦虑症的危险因素,具有此类特征的患者应常规行焦虑症筛查。更多还原

【Abstract】 Background: Patients with functional dyspepsia( FD) often complicated with anxiety. Recognizing effectively the risk factors of anxiety is helpful for the precise treatment with anti-anxiety drug,which can improve the prognosis of patients.Aims: To explore the clinical characteristics and risk factors of FD patients with anxiety. Methods: A total of 295 FD patients from June 2014 to September 2014 at the Second Xiangya Hospital of Central South University were enrolled.Hamilton Anxiety Rating Scale was used to evaluate the anxiety in FD patients. Risk factors of anxiety in FD patients were analyzed. Results: In this study,the incidence of anxiety was 8. 1%(24/295) in FD patients. Univariate analysis showed that age,disease duration,marriage status,psychosis history and history of administration of psychotropic drugs were related to the anxiety in FD patients( P < 0. 05). Multivariate analysis showed that disease duration,marriage status and psychosis history were the risk factors for anxiety in FD patients( P < 0. 05). Conclusions: Long disease duration,incomplete marriage,and psychosis history are the risk factors for anxiety in FD patients,routine anxiety screening should be carried out in these patients.更多还原