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炎症性肠病免疫发病机制的研究进展

Research advance in the immune pathogenesis of inflammatory bowel disease

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【作者】 张金玲杜光李娟

【Author】 ZHANG Jinling;DU Guang;LI Juan;Department of Pharmacy, Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology;College of Pharmacy, Hubei University of Science and Technology;

【通讯作者】 李娟;

【机构】 华中科技大学同济医学院附属同济医院药学部湖北科技学院药学院

【摘要】 炎症性肠病(inflammatory bowel disease,IBD)是一种特发性、慢性和复发性肠道炎症性疾病,其发病机制受到环境、遗传、感染和免疫因素的影响,近年来随着对IBD免疫机制和药物治疗的不断探索,人们对IBD发病机制的认识越来越深入,现从细胞因子参与IBD的发病机制及药物治疗两方面作一概述。

【Abstract】 Inflammatory bowel disease(IBD) is an idiopathic, chronic and recurrent intestinal inflammatory bowel disease, its pathogenesis is affected by the environment, infection and immune factors. In recent years, with the immune mechanism of IBD and medication continuously exploring, people’s understanding of the pathogenesis of IBD is more and more deeply. This paper reviews the pathogenesis of IBD involving cytokines and drug therapy.

【关键词】 炎症性肠病免疫机制治疗
【Key words】 Inflammatory bowel diseaseImmune mechanismTreatment
【基金】 湖北省自然科学基金面上项目(2017CFB782,2014CKB516);湖北省卫生计生委科研项目(WJ2017M077)
  • 【文献出处】 胃肠病学和肝病学杂志 ,Chinese Journal of Gastroenterology and Hepatology , 编辑部邮箱 ,2019年09期
  • 【分类号】R574
  • 【被引频次】26
  • 【下载频次】1264
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