【摘要】 肠道微生态学研究始于对人体"正常菌群"的认识,经历了"正常菌群"、"正常微生物群"和"微生物组"三个阶段。"肠道微生物群"的深入研究催生了微生态学概念,分子生物学技术的进步推动了微生态学的发展,使肠道微生态学的基础研究和临床研究得到了进一步的发展。人体肠道菌群与消化道形成了微生态关系即微生态系,微生态系对机体的疾病发生和健康维持起重要作用。但微生态系影响机体的生态机制还缺乏充足的基础证据。随着生物技术的发展和大数据时代的到来,肠道微生态的原理、机制诠释会更加明确。更多还原

【Abstract】 The study of intestinal microecology began with the understanding of human normal microbiota, and experienced three phases: normal flora, normal microbiota and microbiome. The formation of the concept of intestinal microecology was prompted by the indepth study of intestinal microbiota, the advancement of molecular biology technology has promoted the development of microecology, which has further developed the basic and clinical research of intestinal microecology. Microecosystem is composed of human intestinal microbiota and digestive tract, which plays an important role in the occurrence of diseases and the maintenance of health. However, the ecological mechanism of microecosystem affecting organism is still lack of sufficient basic evidence. With the development of biotechnology and the arrival of the era of big data, the principle and mechanism of intestinal microecology will be more clearly explained in the future.更多还原