【摘要】 目的:探讨医院焦虑抑郁量表在慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)患者焦虑、抑郁情绪筛查中的应用价值,并评估其信度和效度。方法:应用横断面研究方法,选择COPD住院患者200例,对其进行问卷调查。结果:获得有效问卷189份。医院焦虑抑郁量表(HADS)中焦虑、抑郁亚量表得分分别与焦虑自评量表、抑郁自评量表得分呈正相关(P<0.01);以焦虑自评量表和抑郁自评量表作为诊断"金标准"分别绘制焦虑亚量表和抑郁亚量表的ROC曲线,其曲线下面积分别为0.823(95%CI:0.752～0.881)和0.906 (95%CI:0.847～0.948);医院焦虑抑郁量表总表、焦虑亚量表及抑郁亚量表的内部一致性系数的Cronbach’sα分别为0.89, 0.76, 0.83;HADS得分水平与生活质量指数量表呈负相关,证明了其构念效度(P<0.05)。结论 :医院焦虑抑郁量表可以可靠、有效地筛查COPD患者的焦虑、抑郁情绪,可以提高临床医务人员对患者不良情绪的筛查效能。更多还原

【Abstract】 Objective: To identify the clinical value of hospital anxiety and depression scale(HAD) in screening anxiety and depression of patients with chronic obstructive pulmonary disease(COPD) and test its reliability and validity. Methods:200 cases of patients with COPD hospitalized were enrolled by cross-sectional study. Then questionnaires were performed and analyzed. Results: The study of 189 valid questionnaires showed that the two subscales of HADS had significantly correlations with the self-rating anxiety scale(SAS) and the self-rating depression scale(SDS)(P<0.01). Taking SAS and SDS as the gold standard, the area under of the receiver operating characteristic curve(ROC) of both subscale were 0.823(95%CI:0.752～0.881)and 0.906(95%CI:0.847～0.948), respectively. The Cronbach’s alpha coefcients of HADS and two subscales had been found to be 0.89, 0.76, 0.83 respectively. Conclusion: The HADS could help clinical medical staffs improve the screening efficiency of bad mood as a reliable and valid instrument for the assessment of anxiety and depression in patients with COPD.更多还原