【摘要】 目的研究孕期铁缺乏、缺铁性贫血发病率及早期干预铁缺乏孕妇对妊娠结局影响。方法回顾性选取2017年1月至2018年8月张家港市第一人民医院收治的铁缺乏孕妇1 000例,依据治疗方法分为两组:一组患者服用琥珀酸亚铁缓释片(服用组,n=500),一组患者未服用琥珀酸亚铁缓释片(未服用组,n=500)。比较两组孕妇的主要营养素摄入量,血清血红蛋白(Hb)、血清铁蛋白(SF)、红细胞游离原卜琳(FEP)水平,以及妊娠结局。结果服用组孕妇的子痫前期、妊高征、早产、胎儿宫内发育迟缓、胎盘钙化、新生儿低出生体重发生率分别为6. 6%(33/500)、3. 4%(17/500)、3. 4%(17/500)、0、6. 6%(33/500)、3. 4%(17/500);未服用组孕妇的子痫前期、妊高征、早产、胎儿宫内发育迟缓、胎盘钙化、新生儿低出生体重发生率分别为26. 6%(133/500)、3. 4%(17/500)、6. 6%(33/500)、13. 2%(66/500)、10. 0%(50/500)、16. 6%(83/500)。服用组患者的血清Hb、SF、FEP水平均显著高于未服用组(P <0. 05),子痫前期、胎儿宫内发育迟缓、新生儿低出生体重发生率均显著低于未服用组(P <0. 05),出血量显著少于未服用组(P <0. 05),胎盘重量显著低于未服用组(P <0. 05),新生儿体重显著高于未服用组(P <0. 05)。结论早期干预铁缺乏孕妇能够有效改善妊娠结局。更多还原

【Abstract】 Objective To study the effects of iron deficiency,iron deficiency anemia and early intervention on pregnancy outcome in pregnant women with iron deficiency. Methods 1 000 pregnant women with iron deficiency in Zhangjiagang First People’s Hospital from January 2017 to August 2018 were retrospectly analyzed and divided into two groups by random table method: one group was treated with ferrous succinate sustained-release tablets( taking group,n = 500),the other group was not treated with ferrous succinate sustained-release tablets( non-taking group,n = 500). The main nutrient intake,serum hemoglobin( Hb),serum ferritin( SF),erythrocyte free protoprine( FEP) levels and pregnancy outcomes of pregnant women in the two groups were analyzed. Results The preeclampsia,PIH,preterm birth,intrauterine growth retardation,placental calcification and low birth weight were 6. 6%( 33/500),3. 4%( 17/500),3. 4%( 17/500),0,6. 6%( 33/500),3. 4%( 17/500),and 3. 4%( 17/500). The incidence of intrauterine growth retardation,placental calcification and low birth weight were 26. 6%( 133/500),3. 4%( 17/500),6. 6%( 33/500),13. 2%( 66/500),10. 0%( 50/500) and 16. 6%( 83/500),respectively. The serum Hb,SF and FEP levels of the patients in the taking group were significantly higher( P < 0. 05). The incidence of preeclampsia,intrauterine growth retardation and low birth weight of the taking group were significantly lower( P < 0. 05),the amount of bleeding was significantly less( P <0. 05),the placental weight was significantly lower( P < 0. 05),the neonatal weight was significantly higher than the non-taking group( P <0. 05). Conclusion Early intervention of iron deficiency pregnant women can effectively improve pregnancy outcomes.更多还原