【摘要】 目的 :探讨持续非卧床腹膜透析(CAPD)患者腹膜透析相关性腹膜炎(PDAP)发生的相关因素、分析腹膜炎的致病菌特点、药物敏感性和临床转归。方法 :回顾性分析2012年5月至2017年10月福建医科大学附属龙岩第一医院肾内科收治的168例次PDAP患者的病原学、病原学特点、疗效以及转归。结果 :PDAP最主要的相关因素是操作污染。168例次PDAP中132例次培养结果阳性。其中革兰阳性菌78例次(59.09%)、革兰阴性菌31例次(23.48%)、真菌14例次(10.6%)、混合感染9例次(6.82%)。结论 :PDAP的发生率与操作不规范、营养不良密切相关,病原学仍以革兰阳性菌为主,真菌感染患者退出率高。更多还原

【Abstract】 Objective: To investigate the factors related to the occurrence of peritoneal dialysis-associated peritonitis(PDAP) in patients undergoing continuous ambulatory peritoneal dialysis(CAPD), and analyze their pathogenic bacteria, drug sensitivity and clinical outcome. Methods: The etiology, pathogenic characteristics, efficacy and outcome of 168 patients with PDAP treated in our hospital were retrospectively analyzed. Results: The main factor related to PDAP was operational pollution.Among the 168 patients with PDAP, 132 patients showed positive results in microbial culture, including 78 cases(59.09%)infected by gram-positive bacteria, 31 cases(23.48%) by gram-negative bacteria, 14 cases(10.6%) by fungi and 9 cases(6.82%)by mixed infections. Conclusion: The incidence of PDAP is closely related to non-standard operation and malnutrition. Grampositive bacteria are still the main pathogens and the withdrawal rate of patients with fungal infection is high.更多还原