【摘要】 目的 探讨改良型血栓抽吸导管治疗急性下肢深静脉血栓(DVT)的临床疗效及安全性。方法 将符合入组标准的35例急性下肢DVT患者随机分为实验组及对照组。充分术前准备。实验组18例，术中用改良型抽吸导管抽吸后辅以尿激酶溶栓及常规抗凝；对照组17例，术中用美国COOK公司8F血管长鞘抽吸后辅以尿激酶溶栓及常规抗凝。对2组患者治疗前后血管通畅率、下肢周径及并发症等进行观察比较。结果 实验组治疗后血管通畅率Ⅳ级(通畅率为0%)0例，Ⅲ级(通畅率<50%)1例5.56%,Ⅱ级(通畅率>50%)17例94.44%;对照组治疗后血管通畅率Ⅳ级4例23.53%,Ⅲ级9例52.94%,Ⅱ级4例23.53%,出院时患肢膝上、下15 cm处周径差均小于入院时；各组治疗前后均有统计学意义(均P<0.05)。2组均无并发症发生。结论 改良型抽吸导管抽吸下肢急性期DVT是一种安全、有效的治疗手段，抽吸效率高，并发症少，值得临床推广应用。更多还原

【Abstract】 Objective To investigate the thrombus clinical curative effect and practical value in treatment of deep vein thrombosis(DVT) by using modified aspiration catheter.Methods A total of 35 patients who met the diagnostic criteria of DVT were randomly assigned into experimental and control groups.After a sufficient preoperative preparation, the patients were divided into the experimental group(n=18,using modified aspiration catheter with subsequent urokinase thrombolysis and conventional anticoagulation therapy) and the control group [n=17,using the 8F vascular sheaths(COOK,USA) during the procedure, subsequent urokinase thrombolysis and conventional anticoagulation therapy].The patency of vessels, the perimeter difference and the complication were documented.The results were compared between the two groups.Results In experimental group, thrombus removal of grade Ⅳ(removal rate less than 0%) was 0% in 0 case, grade Ⅲ(removal rate less than 50%) was 5.56% in 1 case, grade Ⅱ(removal rate greater than 50%) was 94.44% in 17 cases.In control group, thrombus removal of grade Ⅳ was 23.53% in 4 cases, grade Ⅲ was 52.94% in 9 cases, grade Ⅱ was 23.53% in 4 cases.The differences of the leg circumference of the affected extremities at 15 cm above and below the knee joint at time of discharge were all less than those at admission.The differences in both preoperative and postoperative data between the two groups were statistically significant(both P<0.05).No serious complications were found in two groups.Conclusion Using modified aspiration catheter treating DVT is a safe and effective method, which has high suction efficiency and few complications.Therefore, it is worthy to be recommended.更多还原