【摘要】 目的 分析艾滋病即获得性免疫缺陷综合征(AIDS)患者肝脏CT表现与肝脏功能酶指标的变化，探讨两者之间的关系。方法 回顾性分析2012年10月至2016年3月进行肝脏MSCT平扫+增强扫描及肝功能生化检查的AIDS患者58例，对其肝脏CT表现、肝功能检验资料进行观察统计分析。结果 按肝脏CT表现分4组：1组为肝实质弥漫性无强化密度减低(20例);2组为肝实质多发大小不等的结节状、片状无强化低密度灶(14例);3组为肝实质多发大小不等结节状、片状有强化低密度灶(15例);4组为肝脏CT平扫+增强未见异常(9例);1组肝脏生化指标异常例数最多，且1组天门冬氨酸氨基转移酶(AST)、丙氨酸氨基转移酶(ALT)测值均明显高于其他组，差异有统计学意义(P<0.05),1组γ谷氨酰转肽酶(GGT)测值高于其他组，但差异无统计学意义(P>0.05)。结论 AIDS肝功能异常患者肝脏CT表现各异，CT所见以肝脏无强化弥漫性密度减低表现为多见，肝功能损害较明显，对AIDS肝功能损害评价有一定参考意义。更多还原

【Abstract】 Objective To explore the relationship between the CT changes of the liver and liver function biomarker abnormalities in HIV/AIDS patients.Methods We retrospectively analyzed 58 cases of HIV/AIDS who underwent plain and enhanced MSCT scans of the liver with liver function examinations in our hospital from October 2012 to March 2016.The collected data were then statistically analyzed to establish whether there were any relationships or not between them.Results The patients were divided into 4 groups according to the CT findings.In Group 1,the density of liver parenchyma decreased diffusely on plain CT and no enhancement on enhanced CT(20/58).In Group 2,liver parenchyma showed multi-nodular, lamellar low density lesions on plain CT and no enhancement in enhanced CT(14/58).In Group 3,liver parenchyma showed multiple nodular, lamellar and low-density lesions on plain CT scan and enhancement on enhanced CT(15/58).The plain and enhanced CT of Group 4 did not reveal any obvious abnormalities(9/58).The liver biochemical marker index abnormalities were highest in Group 1,with the aspartate aminotransferase(AST) and alanine aminotransferase(ALT) values significantly higher than those in other groups(P<0.05).The GGT value of Group 1 was also higher than that of the other groups, however, the difference was not statistically significant(P>0.05). Conclusion The liver function of HIV/AIDS patients is different, with significantly higher degree of impairments when compared with normal people.These patients with the density of liver parenchyma decreased diffusely in CT scan, and no enhancement in enhanced scan were more common, their liver function impairment were more obvious, supporting the abnormal results of the liver biomarker tests.更多还原