【摘要】 目的探讨腹主动脉旁淋巴结切除术在子宫内膜癌治疗中的临床应用价值。方法选取行手术治疗确诊为子宫内膜癌患者80例作为研究对象,按照术中是否行腹主动脉旁淋巴结清扫分为对照组及研究组,各40例。对照组行传统开腹主动脉旁淋巴结切除术,研究组行腹主动脉旁淋巴结切除术。对比分析2组患者的围手术期手术时间、住院时间、术中出血量、术后排气时间等指标,治疗前后CA125、CEA、CA199肿瘤标志物的改善情况,以及患者的淋巴结切除数量、术后并发症发生率。结果研究组的围手术期指标相较对照组,差异具有统计学意义(P <0. 05);研究组的淋巴结切除数量相较对照组明显较多(P <0. 05)。2组患者治疗前CA125、CEA、CA199肿瘤标志物并无显著差异(P>0. 05),治疗后均有所降低(P <0. 05)。研究组的术后并发症发生率相较对照组略多,但差异不具有统计学意义(P>0. 05)。结论应用腹主动脉旁淋巴结切除术治疗子宫内膜癌可以取得显著疗效,但是会增加术后的下肢淋巴水肿以及淋巴囊肿发生率,需要结合患者的自身实际情况在临床中推广运用。更多还原

【Abstract】 Objective The clinical value of para aortic lymph node dissection in the treatment of endometrial cancer.Methods 80 patients with endometrial cancer diagnosed by surgery were selected for the study. Patients were divided into 2 groups according to whether they underwent para aortic lymph node dissection. The control group underwent traditional open paraaortic lymphadenectomy,while the study group underwent para-aortic lymphadenectomy. The perioperative operation time,hospital stay,intraoperative bleeding volume and postoperative exhaust time of the 2 groups were compared and analyzed,The improvement of CA125,CEA and CA199 tumor markers before and after treatment. as well as the number of lymph node resection and the incidence of postoperative complications. Results The study found that the perioperative indicators of the study group were significantly better than those of the control group,and the difference between the 2 groups was statistically significant( P < 0. 05). The number of lymph node resection in the study group was significantly more than that of the control group,and the difference between the 2 groups was statistically significant( P < 0. 05). The incidence of postoperative complications in the study group was slightly higher than that of the control group,There was no significant difference in CA125,CEA and CA199 tumor markers between the 2 groups before treatment( P > 0. 05),but they decreased after treatment( P < 0. 05),and there was no significant difference between the 2 groups( P > 0. 05). Conclusion It is found that abdominal para-aortic lymphadenectomy is effective in the surgical treatment of endometrial cancer. The incidence of complications was reduced,but the incidence of lower limb lymphedema and Lymphocyst is increased. It is necessary to promote the use of patients in their clinical practice.更多还原