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结直肠癌伴肝转移行腹腔镜手术治疗的安全性与有效性
Study of Safety and Effectiveness with Laparoscopic Surgery in Colorectal Cancer with Liver Metastasis
【摘要】 目的探讨腹腔镜手术治疗结直肠癌伴随肝转移的安全性和有效性。方法选取结直肠癌伴随肝转移患者96例为研究对象,分为观察组和对照组。对照组患者行开腹手术治疗,观察组患者行腹腔镜手术治疗,分析2组患者手术时间、出血量及术后恢复情况等。结果 2组患者均顺利完成手术,观察组患者手术时间为(184. 6±18. 4) min,与对照组的(172. 5±17. 6) min差异不明显(P> 0. 05);观察组术中出血量[(56. 4±12. 9) ml]显著少于对照组[(83. 6±20. 4) ml](P <0. 05)。观察组患者术后肛门排气时间[(59. 6±5. 4) h]、住院时间[(11. 7±3. 0) d]和术后化疗时间[(26. 3±4. 9) d]均显著短于对照组肛门排气时间[(85. 9±9. 9) h]、住院时间[(14. 1±2. 7) d]和术后化疗时间[(30. 5±3. 7) d](P <0. 05)。2组患者疗效差异不明显(P> 0. 05)。结论腹腔镜手术治疗结直肠癌伴肝转移患者安全性高,与开腹手术相比,能够减少出血量和创伤,效果明显,具有应用价值。
【Abstract】 Objective To investigate the effect of safety and effectiveness with laparoscopic surgery in colorectal cancer with liver metastasis. Methods 96 cases of patients with colorectal cancer with liver metastasis were selected,patients were randomly divided into observation group and control group. Control group patients were given laparotomy,observation group patients were taken trentment of laparoscopic surgery,Two groups of patients with operation time,amount of blood loss postoperative recovery of patients were compared. Results Two groups of patients were successfully completed surgery,there was no significant difference between the operation time( 184. 6 ± 18. 4) min and the control group( 172. 5 ± 17. 6) min in the observation group( P > 0. 05),the intraoperative blood loss( 56. 4 ± 12. 9) ml was significantly less than that in the control group( 83. 6 ± 20. 4)ml( P < 0. 05). The intraoperative blood loss( 56. 4 ± 12. 9) ml was significantly less than that in the control group( 83. 6 ±20. 4) ml( P < 0. 05). The time of postoperative anal exhaust( 59. 6 ± 5. 4) h,hospitalization time( 11. 7 ± 3. 0) d and postoperative chemotherapy time( 26. 3 ± 4. 9) d in the observation group were significantly shorter than in the control group( 85. 9 ±9. 9) H,hospital stay( 14. 1 ± 2. 7) d and postoperative chemotherapy time( 30. 5 ± 3. 7) days( P < 0. 05). There was no significant difference between the two groups( P > 0. 05). Conclusion Laparoscopic surgery for colorectal cancer with liver metastasis in patients with high safety,compared with open surgery,can reduce the amount of bleeding and trauma,the effect is obvious,has the value of application.
【Key words】 Colorectal cancer; Liver metastasis; Laparoscopy; Operation time; Amount of Bleeding;
- 【文献出处】 实用癌症杂志 ,The Practical Journal of Cancer , 编辑部邮箱 ,2019年02期
- 【分类号】R735.34
- 【被引频次】5
- 【下载频次】61