【摘要】 目的:观察低频脉冲电磁场(PEMFs)联合腰背肌训练对糖尿病性骨质疏松中医证候积分及IL-6、TNF-α的影响。方法:选取2型糖尿病骨质疏松患者64例,随机分为两组,联合组及对照组,两组基础治疗均给予左归丸口服,联合组在此基础上给予PEMFs联合腰背肌训练,对照组仅予基础治疗,观察不同治疗方法对两组中医证候积分以及IL-6及TNF-α的影响。结果:联合组经PEMFs联合腰背肌训练后,症状改善明显,中医证候积分较前降低,总有效率93.75%,较对照组37.5%有统计学差异。联合组治疗后TNF-α、IL-6[(8.16±0.63)pg/ml、(4.29±0.32)pg/ml]较治疗前降低[(9.36±0.32)pg/ml、(4.70±0.51)pg/ml],组内及组间比较均有明显统计学意义。结论:炎症参与2型糖尿病骨质疏松的进程,PEMFs联合腰背肌训练对骨代谢有保护作用,结合中医理论基础,更好地确证了"骨肉不相亲"的科学内涵。更多还原

【Abstract】 Objective:To observe the effect of pulsed electromagnetic field(PEMFs) combined with lower back muscle training on the level of IL-6 and TNF-α in patients with diabetic osteoporosis. Methods:64 patients with diabetic osteoporosis were divided into two groups,combination group and control group,Zuogui pills were given to 2 groups,combination group also combination of PEMFs and lower back muscle training. To evaluate the two groups of the levels of IL-6,TNF-α and the TCM syndrome points. Results:After combination of PEMFs and lower back muscle training,the syndrome scores of TCM were obviously improved compared with the previous,the total efficiency 93.75% vs 37.5% of control group. After the treatments,TNF-α、IL-6[(8.16±0.63) pg/ml、(4.29±0.32) pg/ml]were lower than before[(9.36±0.32) pg/ml、(4.70±0.51)pg/ml] in the combination group.There were statistically decreased compared with before and between groups. Conclusion:The process of osteoporosis in cases with type 2 diabetes may involve in inflammation,PEMFs combined with lower back muscle training play a protective role on bone metabolism,given the theoretical basis of TCM,it’s more conclusive for the scientific implication of disharmony between bone and muscle.更多还原