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西安市某医院成人与儿童血清25羟基维生素D水平的研究

Study on Serum 25-hydroxyvitamin D Levels in Adults and Children in a Hospital in Xi’an

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【作者】 任晓兵徐蓓陈广福张婕钰朱克修

【Author】 REN Xiao-bing;XU Bei;CHEN Guang-fu;ZHANG Jie-yu;ZHU Ke-xiu;Xi’an Jiaotong University Health Science Center;Laboratory of Gynecology, Xi’an Gaoxin Hospital;Department of Laboratory Medicine, Xi’an Children’s Hospital;Department of Gynecology and Obstetrics, The First Affiliated Hospital of Xi’an Jiaotong University;

【通讯作者】 朱克修;

【机构】 西安交通大学医学部西安高新医院妇科实验室西安市儿童医院检验科西安交通大学第一附属医院妇产科

【摘要】 目的:比较西安市某医院不同年龄段的成人与儿童血清25羟基维生素D(25-OH-VD)水平,并探讨其水平与年龄之间的关系。方法:收集2017年1月-2018年1月西安高新医院检测血清25-OH-VD的2116例样本,比较成人与儿童血清中25-OH-VD水平的差异,分析成人与儿童血清中25-OH-VD水平与年龄之间的关系。结果:儿童组健康人群、低水平人群血清25-OH-VD水平均高于成人组(P<0.05);儿童组健康人群、低水平人群血清25-OH-VD水平与年龄呈负相关(P<0.05),成人组健康人群血清25-OH-VD水平与年龄呈正相关(P<0.05)。结论:西安市某医院的儿童血清25-OH-VD水平高于成人,且成人与儿童的血清25-OH-VD水平与年龄存在一定的关系,有必要建立不同的参考区间,为临床诊治提供更精确的依据。

【Abstract】 Objective: To compare the serum 25-hydroxyvitamin D(25-OH-VD) levels in adults and children with different ages in a hospital in Xi’an, and to explore the relationship between the levels and age. Methods: A total of 216 serum samples of 25-OH-VD in Xi’an Gao-xin Hospital from January 2017 to January 2018 were collected. The serum 25-OH-VD levels were compared between adults and children, the relationship between serum 25-OH-VD levels and age in adults and children was analyzed. Results: Serum 25-OH-VD levels in healthy people and low-level people in the children group were higher than those in the adult group(P<0.05). Serum 25-OH-VD levels in healthy and low-level children were negatively correlated with age(P<0.05). Serum 25-OH-VD levels in healthy people in the adults group was positively correlated with age(P<0.05). Conclusion: The serum 25-OH-VD levels of children in a hospital in Xi’an are higher than that of adults, and there is a certain relationship between the serum 25-OH-VD levels of adults and children and age.It is necessary to establish different reference intervals to provide more accurate basis for clinical diagnosis and treatment.

【关键词】 西安25羟基维生素D儿童成人年龄
【Key words】 Xi’an25-hydroxyvitamin DChildrenAdultAge
【基金】 国家自然科学基金项目(31370193)
  • 【文献出处】 现代生物医学进展 ,Progress in Modern Biomedicine , 编辑部邮箱 ,2019年20期
  • 【分类号】R153.2;R446.1
  • 【被引频次】1
  • 【下载频次】102
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