【摘要】 目的观察中西医结合快速康复踏板在腹腔镜辅助经腹会阴联合直肠癌根治术术后预防下肢静脉血栓中的作用。方法将160例腹腔镜辅助经腹会阴联合直肠癌根治术术后患者随机分为治疗组和对照组,每组80例。对照组于术后采用间歇性充气压力泵干预,治疗组于术后采用中西医结合快速康复踏板干预。两组疗程均为7日,观察下肢静脉血栓及不良反应发生率,比较股总静脉内径(D_V)、呼气末股总静脉最大流速(Vmax)、股总静脉内径/股总动脉内径(D_V/D_A)、D-二聚体(D-D)、凝血酶原时间(PT)的变化情况。结果①组间下肢静脉血栓发生率比较,治疗组(15.00%)明显低于对照组(32.50%),差异有统计学意义(P=0.009<0.05)。②组间治疗后比较,治疗组D_V、D_V/D_A水平明显低于对照组(P=0.027、0.000<0.05),治疗组Vmax水平明显高于对照组(P=0.014<0.05)。③组间治疗后比较,治疗组D-D、PT水平明显低于对照组(P=0.000<0.05)。④组间不良反应发生率比较,差异无统计学意义(P=0.311>0.05)。结论中西医结合快速康复踏板可有效降低腹腔镜辅助经腹会阴联合直肠癌根治术术后患者下肢静脉血栓发生率,改善凝血功能及股总静脉生理指标,且具有较好的安全性。更多还原

【Abstract】 Objective To observe the role of fast-rehabilitation pedal in integrated traditional Chinese and Western medicine therapy in preventing postoperative venous thrombosis of the lower extremities in patients with laparoscopic-assisted transabdominal perineal radical resection for rectal cancer. Methods 160 patients after laparoscopic-assisted transabdominal perineal radical resection for rectal cancer were randomly assigned into treatment group and control group, 80 patients in each group. To prevent venous thrombosis of the lower extremities, patients in the control group were treated with intermittent pneumatic pressure pump and those in the treatment group were treated with fast-rehabilitation pedal. Both groups were treated for 7 days. The incidence of venous thrombosis and adverse reactions in the lower extremities was observed. The internal diameter of the common femoral vein(D_V), maximum flow rate of the common femoral vein at the end of expiration(Vmax), internal diameter of the common femoral vein/internal diameter of the common femoral artery(D_V/D_A), D-dimer(D-D) and prothrombin time(PT) were compared. Results ①The incidence of venous thrombosis in the lower extremities was significantly lower in the treatment group(15.00%) than in the control group(32.50%), with statistically significant difference(P=0.009<0.05). ②After treatment, the levels of D_V and D_V/D_A were significantly lower in the treatment group than in the control group(P=0.027, 0.000<0.05). The Vmax level was significantly higher in the treatment group than in the control group(P=0.014<0.05).③After treatment, the levels of D-D and PT were significantly lower in the treatment group than in the control group(P=0.000<0.05). ④There was no significant difference in the incidence of adverse reactions between the groups(P=0.311>0.05). Conclusion Fast-rehabilitation pedal can effectively reduce the incidence of postoperative lower extremity venous thrombosis in patients with laparoscopic-assisted transabdominal perineal radical resection for rectal cancer, improve coagulation function and physiological index of the common femoral vein, and has good safety.更多还原