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骆驼蓬生物碱抗炎和免疫调节的药理作用机制研究进展
Pharmacological mechanism of anti-inflammatory and immunomodulatory effects of alkaloids from Peganum harmala: Research advances
【摘要】 综述骆驼蓬生物碱的抗炎和免疫作用机制研究进展。骆驼蓬属植物的化学成分主要为生物碱类成分,具有DNA拓扑异构酶活性及细胞毒作用,对淋巴细胞、细胞因子有免疫作用,同时具有抗炎和镇痛作用。
【Abstract】 This paper reviews the progress of anti-inflammatory and immune effects of the alkaloids extracted from Peganum harmala. The chemical constituents of Peganum are mainly alkaloids,which have the following functions: DNA topoisomerase activity and cytotoxicity; immunity to lymphocytes and cytokines; anti-inflammatory and analgesic effects.
【关键词】 骆驼蓬;
生物碱;
免疫;
抗炎;
镇痛;
细胞毒;
药理作用;
综述;
【Key words】 Peganum harmala; alkaloids; immunity; anti-inflammatory; analgesia; cytotoxicity; pharmacological effects; review;
【Key words】 Peganum harmala; alkaloids; immunity; anti-inflammatory; analgesia; cytotoxicity; pharmacological effects; review;
【基金】 上海市浦东新区卫计委资助项目(PWZzb2017-14)
- 【文献出处】 上海中医药杂志 ,Shanghai Journal of Traditional Chinese Medicine , 编辑部邮箱 ,2019年02期
- 【分类号】R285.5
- 【被引频次】14
- 【下载频次】449