【摘要】 目的研究孤独症谱系障碍(ASD)男童社交技能结构特点及其与血清睾酮的相关性。方法对2016年3月至2017年12月在深圳罗湖区妇幼保健院就诊的200名4～11岁ASD男童及从该地区所属幼儿园和小学招募的正常对照男童,进行血清睾酮检测,用马特森儿童社会技能评价量表(MESSY)评估社交技能中适当社交行为、敌对社交行为及不恰当自信/过度自信等3个维度。用儿童同理心-系统化商数问卷(EQ-SQ)评估共情商(EQ)和系统化商(SQ)。分析MESSY量表结果与血清睾酮水平及共情能力的相关性。结果 ASD男童社交技能明显差于正常儿童(t=5.83,P<0.01),适当行为少于正常儿童(t=2.60,P<0.05),敌对行为以及不恰当自信/过度自信行为多于正常儿童,差异均有显著性。ASD儿童不恰当自信/过度自信行为与共情呈负相关(r=-0.28,P<0.05),与睾酮水平呈正相关(r=0.33,P<0.05),适当行为和敌对行为与共情和睾酮水平无明显相关(均P<0.05)。结论 ASD男童具有较多的不恰当自信/过度自信行为以及敌对行为等社交障碍,并且受睾酮水平和共情能力影响,需在治疗中加以重视。更多还原

【Abstract】 ObjectiveTo study the structural characteristics of social skills of boys with autism spectrum disorder(ASD) and their correlation with serum testosterone level. Methods Serum testosterone level of 200 boys aged 4-11 with ASD and that of normal control boys were tested, and the Matson evaluation of social skills with youngsters(MESSY) was used to assess three dimensions of social skills: appropriate social behavior, hostile social behavior, and inappropriate self-confidence/overconfidence. The empathy quotient(EQ) and systemizing quotient(SQ) of the boys were assessed with the children’s empathy quotient and systemizing quotient(the Children EQ-SQ). The correlation between the results of the MESSY questionnaire and the serum testosterone level and empathy ability was analyzed. Results The social skills of boys with ASD were significantly worse(t=5.83,P<0.01), appropriate actions were less(t=2.60,P<0.05), and the hostile social behavior and inappropriate confidence/overconfidence behavior were more than normal boys with significant differences. The inappropriate confidence/overconfidence behavior was negatively correlated with empathy ability of ASD boys(r=-0.28,P<0.05) but positively correlated with testosterone level(r=0.33,P<0.05). Appropriate behavior and hostility were not significantly correlated with empathy and testosterone levels(both P<0.05). Conclusion ASD boys have more inappropriate confidence/overconfidence behavior and hostile behavior, and their behavior are influenced by testosterone levels and empathy capacity, which needs caution in the treatment.更多还原