【摘要】 目的:研究结直肠癌患者手术治疗后进行早期肠内营养的临床效果。方法:纳入2017年12月—2018年10月于青岛市市立医院东院普外一科接受治疗的结直肠癌患者80例进行研究,采用随机数字表法将患者分为早期肠内营养组(EEN组)、肠外营养组(PA组),EEN组40例,PA组42例。观察两组营养指标、临床指标、免疫指标、康复情况、并发症发生率。结果:EEN组转铁蛋白(TF)、血清白蛋白(PA)、前白蛋白(ALB)水平均优于PA组,差异有统计学意义(P<0.05);EEN组体重下降情况、拆线时间、住院费用均优于PA组,差异有统计学意义(P<0.05);除补体水平外,EEN组各项免疫指标均优于PA组,差异有统计学意义(P<0.05);EEN组术后排气时间、下床时间、住院时间均优于PA组,差异有统计学意义(P<0.05);EEN组患者腹胀、高糖血症、切口感染、肺部感染等并发症明显少于PA组,差异有统计学意义(P<0.05)。结论:结直肠癌患者手术治疗后进行EEN的临床效果显著,既可提高康复情况,又可改善营养指标,值得借鉴。更多还原

【Abstract】 Objective:To study the clinical effect of early enteral nutrition in patients with colorectal cancer after surgical treatment. Methods:A total of 80 patients with colorectal cancer who were treated in the first department of general surgery of Qingdao municipal hospital from December 2017 to October 2018 were enrolled in this study. They were divided into the early enteral nutrition group(EEN group), the parenteral nutrition group(PA group), EEN group(40 cases) and PA group(42 cases). The nutritional index, clinical index,immune index, recovery status and complication rate of the two groups were observed. Results:The levels of transferrin(TF), serum albumin(PA) and prealbumin(ALB) in EEN group were all higher than those in PA group, with statistically significant differences(P<0.05). Weight loss, suture removal time and hospitalization cost were all higher in EEN group than in PA group, with statistically significant differences(P<0.05). Aside from complement level differences from PA group in terms of statistical significance, EEN group performed better in all the other mutation indicators with statistical significance(P<0.05). Exhaust time, bed time and hospitalization time were all better in the EEN group than in PA group, and the difference was statistically significant(P<0.05). Complications such as abdominal distension, hyperglycemia, incision infection and pulmonary infection were significantly less in EEN group than in PA group, with statistically significant differences(P<0.05). Conclusion:EEN treatment after surgery in patients with colorectal cancer has a significant clinical effect, which can not only improve the rehabilitation situation, but also improve the nutritional indicators,which is worthy of reference.更多还原